In the 10 years since our previous International Union of Basic and Clinical Pharmacology
report on the nomenclature and classification of adenosine receptors, no developments …

Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are
important signaling molecules that mediate diverse biological effects via cellsurface …

Four adenosine receptors have been cloned and characterized from several mammalian
species. The receptors are named adenosine A1, A2A, A2B, and A3. The A2A and A2B …

There has been an exponential growth in interest n purinoceptors since the potent effects of
purines were first reported in 1929 and purinoceptors defined in 1978. A distinction between …

“Receptors recognize a distinct chemical entity and translate information from that entity into
a form that the cell can read to alter its state”(Kenakin et al., 1992). Even though the …

A. Cellular and Subcellular Localization B. Pharmacological Tools to Study Adenosine
Receptors C. Signaling Via Adenosine Receptors D. Regulation of Receptor Expression and …

Since the discovery of adrenomedullin in 1993 several hundred papers have been
published regarding the regulation of its secretion and the multiplicity of its actions. It has …

Four adenosine receptors have been cloned from many mammalian and some non-
mammalian species. In each case the translated part of the receptor is encoded by two …

A cDNA fragment homologous to other G protein-coupled receptors was isolated from rat
brain using the PCR method and demonstrated to be abundantly expressed in striatum …

We have previously reported the selective amplification of several rat striatal cDNA
sequences that encode guanine nucleotide-binding regulatory protein (G protein)-coupled …