The human intestine is a natural environment ecosystem of a complex of diversified and
dynamic microorganisms, determined through a process of competition and natural …

PD-1 (Programmed Cell Death Protein-1) and PD-L1 (Programmed Cell Death Ligand-1)
play a crucial role in regulating the immune system and preventing autoimmunity. Cancer …

Tumor microbiota can produce active metabolites that affect cancer and immune cell
signaling, metabolism, and proliferation. Here, we explore tumor and gut microbiome …

Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …

The relationship between systemic inflammation and tumor-associated bacteria is largely
unknown in colorectal cancer (CRC). The primary aim of this study was to investigate the …

Differences in the average age at cancer diagnosis are observed across countries. We
therefore aimed to assess international variation in the median age at diagnosis of common …

Simple Summary Colorectal cancer (CRC) is one of the most prevalent cancers worldwide.
Due to the absence of specific early symptoms, most of CRC patients are often diagnosed at …

Introduction While modulation of the human adult gut microbiota is a trending strategy to
improve health, the underlying mechanisms are poorly understood. Methods This study …

Colorectal cancer is the second leading cause of cancer-related mortality worldwide.
Numerous pathophysiological mechanisms, such as abnormal cell proliferation, cell …

Colorectal cancer (CRC) is a leading cause of human mortality worldwide. As conventional
anticancer therapy not always being effective, there is growing interest in innovative “drug …