Combined aclidinium bromide and long‐acting beta2‐agonist for chronic obstructive pulmonary disease (COPD)

H Ni, S Moe, Z Soe, KT Myint… - Cochrane Database of …, 2018 - cochranelibrary.com
Background Several dual bronchodilator combinations of long‐acting beta 2‐agonist (LABA)
and long‐acting muscarinic antagonist (LAMA) have been approved for treatment of stable …

The airways' mechanical stress in lung disease: implications for COPD pathophysiology and treatment evaluation

P Santus, M Pecchiari, F Tursi, V Valenti… - Canadian …, 2019 - Wiley Online Library
The airway epithelium stretches and relaxes during the normal respiratory cycle, and
hyperventilation exaggerates this effect, resulting in changes in lung physiology. In fact …

Once-daily single-inhaler versus twice-daily multiple-inhaler triple therapy in patients with COPD: lung function and health status results from two replicate randomized …

GT Ferguson, N Brown, C Compton, TC Corbridge… - Respiratory …, 2020 - Springer
Background The comparative efficacy of inhaled corticosteroid/long-acting muscarinic
antagonist/long-acting β 2-agonist (ICS/LAMA/LABA) triple therapy administered via single …

Recombinant club cell protein 16 (CC16) ameliorates cigarette smoke‑induced lung inflammation in a murine disease model of COPD

M Pang, HY Liu, T Li, D Wang… - Molecular …, 2018 - spandidos-publications.com
Club cell protein (CC16) is expressed primarily by club cells possesses anti‑inflammatory
properties and is located in the bronchiolar epithelium. Previous studies have demonstrated …

High 24-hour respiratory symptoms and low physical activity in the stable copd romanian cohort of space study

F Mihaltan, RM Rajnoveanu, OC Arghir… - … Journal of Chronic …, 2021 - Taylor & Francis
Objective This study assessed the characteristics and the relationship between symptoms in
any part of the 24-hour (24-h) day, physical activity level (PAL), and other clinical and …

Cost-effectiveness of fixed-dose combinations therapies for chronic obstructive pulmonary disease treatment

M Capel, M Mareque, CJ Álvarez, L Lindner… - Clinical Drug …, 2018 - Springer
Abstract Background and Objective Chronic obstructive pulmonary disease (COPD), a
progressive lung disorder associated with decline of respiratory function, affects 10.2% of …

Основные фенотипы хронической обструктивной болезни легких

ЛВ Куколь, ЛИ Арчакова, ЕР Молокова - Медицинский альянс, 2019 - med-alyans.ru
Аннотация Хроническая обструктивная болезнь легких (ХОБЛ) является одной из
основных причин мировой заболеваемости и смертности с тенденцией к росту …

[HTML][HTML] Bronchodilator therapy in patients with chronic obstructive pulmonary disease: what should be considered in clinical practice when choosing a dosing …

ON Titova, NA Kuzubova, AG Kozyrev… - …, 2023 - journal.pulmonology.ru
The use of long-acting bronchodilators is central to the chronic obstructive pulmonary
disease (COPD) therapy. One of the goals of bronchodilation is to reduce the morning …

Бронхолитическая терапия при хронической обструктивной болезни легких: что следует учитывать в клинической практике при выборе режима дозирования …

ОН Титова, НА Кузубова, АГ Козырев… - …, 2023 - journal.pulmonology.ru
Аннотация Применение бронхолитических препаратов длительного действия (ДД)
составляет основу лечения хронической обструктивной болезни легких (ХОБЛ). Одной …

Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT

AD D'Urzo, D Singh, JF Donohue… - … journal of chronic …, 2019 - Taylor & Francis
Background Aclidinium/formoterol 400/12 µg is a twice-daily maintenance bronchodilator for
COPD. This post hoc study evaluated aclidinium/formoterol vs aclidinium 400 µg, formoterol …