Neutrophils at work

WM Nauseef, N Borregaard - Nature immunology, 2014 - nature.com
In this Review we discuss data demonstrating recently recognized aspects of neutrophil
homeostasis in the steady state, granulopoiesis in'emergency'conditions and interactions of …

Stem cell homing: From physiology to therapeutics

JL Liesveld, N Sharma, OS Aljitawi - Stem Cells, 2020 - academic.oup.com
Stem cell homing is a multistep endogenous physiologic process that is also used by
exogenously administered hematopoietic stem and progenitor cells (HSPCs). This multistep …

Biomaterial-driven in situ cardiovascular tissue engineering—a multi-disciplinary perspective

TB Wissing, V Bonito, CVC Bouten… - NPJ Regenerative …, 2017 - nature.com
There is a persistent and growing clinical need for readily-available substitutes for heart
valves and small-diameter blood vessels. In situ tissue engineering is emerging as a …

Role of inflammation in benign gynecologic disorders: from pathogenesis to novel therapies

A AlAshqar, L Reschke, GW Kirschen… - Biology of …, 2021 - academic.oup.com
Emerging evidence supports the notion that inflammation fosters the development of
common benign gynecologic disorders, including uterine leiomyoma, endometriosis, and …

Intravital imaging reveals motility of adult hematopoietic stem cells in the bone marrow niche

S Upadhaya, O Krichevsky, I Akhmetzyanova… - Cell Stem Cell, 2020 - cell.com
Adult mammalian hematopoietic stem cells (HSCs) reside in the bone marrow (BM) but can
be mobilized into blood for use in transplantation. HSCs interact with BM niche cells that …

Transforming growth factor‐β1 in intrauterine adhesion

A Abudukeyoumu, MQ Li, F Xie - American Journal of …, 2020 - Wiley Online Library
Intrauterine adhesion (IUA), led by trauma to the basal layer, can prevent the endometrium
from growing, resulting in complications in females, such as infertility and amenorrhea …

Successful hematopoietic stem cell mobilization and apheresis collection using plerixafor alone in sickle cell patients

EB Esrick, JP Manis, H Daley, C Baricordi… - Blood …, 2018 - ashpublications.org
Novel therapies for sickle cell disease (SCD) based on genetically engineered autologous
hematopoietic stem and progenitor cells (HSPCs) are critically dependent on a safe and …

Concise review: CXCR4/CXCL12 signaling in immature hematopoiesis—lessons from pharmacological and genetic models

D Karpova, H Bonig - Stem Cells, 2015 - academic.oup.com
Dominant, although nonexclusive roles of CXCR4 and its chief ligand CXCL12 in bone
marrow (BM) retention and preservation of the relative quiescence of hematopoietic …

The good and bad faces of the CXCR4 chemokine receptor

J Teixido, M Martinez-Moreno, M Diaz-Martinez… - … International Journal of …, 2018 - Elsevier
Chemokines are chemotactic cytokines that promote cell migration and activation under
homeostatic and inflammatory conditions. Chemokines bind to seven transmembrane …

Stem cells derived from “inflamed” and healthy periodontal ligament tissues and their sheet functionalities: a patient‐matched comparison

HN Tang, Y Xia, Y Yu, RX Wu, LN Gao… - Journal of Clinical …, 2016 - Wiley Online Library
Aim The aim of this study was to compare the properties of stem cells derived from
“inflamed” and healthy periodontal ligament (PDL) tissues from patient‐matched groups …