The mechanism of ferroptosis and its related diseases
S Feng, D Tang, Y Wang, X Li, H Bao, C Tang… - Molecular …, 2023 - Springer
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …
Frequency of Germline and Somatic BRCA1 and BRCA2 Mutations in Prostate Cancer: An Updated Systematic Review and Meta-Analysis
AA Valsecchi, R Dionisio, O Panepinto, J Paparo… - Cancers, 2023 - mdpi.com
Simple Summary Our updated systematic review and meta-analysis investigates the
frequency of germline and somatic BRCA1 and BRCA2 mutations in patients with prostate …
frequency of germline and somatic BRCA1 and BRCA2 mutations in patients with prostate …
Potential pathogenic germline variant reporting from tumor comprehensive genomic profiling complements classic approaches to germline testing
N Tung, KC Dougherty, ES Gatof, K DeLeonardis… - npj Precision …, 2023 - nature.com
Existing guidance regarding clinically informed germline testing for patients with cancer is
effective for evaluation of classic hereditary cancer syndromes and established gene/cancer …
effective for evaluation of classic hereditary cancer syndromes and established gene/cancer …
DNA damage response and mismatch repair gene defects in advanced and metastatic prostate cancer
D Akhoundova, P Francica, S Rottenberg… - Advances in anatomic …, 2024 - journals.lww.com
Alterations in DNA damage response (DDR) and related genes are present in up to 25% of
advanced prostate cancers (PCa). Most frequently altered genes are involved in the …
advanced prostate cancers (PCa). Most frequently altered genes are involved in the …
Synthetic Lethality by Co-Inhibition of Androgen Receptor and Polyadenosine Diphosphate-Ribose in Metastatic Prostate Cancer
M Calabrese, I Saporita, F Turco, S Gillessen… - International Journal of …, 2023 - mdpi.com
Androgen receptor pathway inhibitors (ARPI) and polyadenosine diphosphate-ribose
inhibitors (PARPi) are part of the standard of care in patients with metastatic castration …
inhibitors (PARPi) are part of the standard of care in patients with metastatic castration …
Development of PARP inhibitors in advanced prostate cancer
MT Bourlon, P Valdez, E Castro - Therapeutic Advances in …, 2024 - journals.sagepub.com
The relatively high prevalence of alterations in the homologous recombination repair (HRR)
pathway described in advanced prostate cancer provides a unique opportunity to develop …
pathway described in advanced prostate cancer provides a unique opportunity to develop …
Newly developed MEIS inhibitor selectively blocks MEISHigh prostate cancer growth and induces apoptosis
Prostate cancer (PCa) is the second most diagnosed cancer in males. Understanding the
molecular mechanism and investigation of novel ways to block PCa growth or metastasis …
molecular mechanism and investigation of novel ways to block PCa growth or metastasis …
[HTML][HTML] Molecular Genetics of Prostate Cancer and Role of Genomic Testing-Beyond the Abstract
Prostate cancer is the most common cancer among men and is a relevant cause of morbidity
and cancer-related mortality. On the molecular level, prostate cancer is characterized by …
and cancer-related mortality. On the molecular level, prostate cancer is characterized by …
[引用][C] Prostate Cancer Genomic Testing: When Sequencing Is Not Sufficient and Germline Testing Is Necessary.
MF Jacobs, SE Greenberg - European urology, 2022 - europepmc.org
Prostate Cancer Genomic Testing: When Sequencing Is Not Sufficient and Germline Testing
Is Necessary. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …
Is Necessary. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe …