Osteopontin in vascular disease: Friend or foe?
ZSY Lok, AN Lyle - Arteriosclerosis, thrombosis, and vascular …, 2019 - Am Heart Assoc
Inflammatory cytokines are necessary for an acute response to injury and the progressive
healing process. However, when this acute response does not resolve and becomes …
healing process. However, when this acute response does not resolve and becomes …
[HTML][HTML] The extracellular matrix as modifier of neuroinflammation and recovery in ischemic stroke and intracerebral hemorrhage
Stroke is the second leading cause of death worldwide and has two major subtypes:
ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of …
ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of …
Single-cell RNA-seq reveals the transcriptional landscape in ischemic stroke
Ischemic stroke (IS) is a detrimental neurological disease with limited treatments options. It
has been challenging to define the roles of brain cell subsets in IS onset and progression …
has been challenging to define the roles of brain cell subsets in IS onset and progression …
Profiling the neurovascular unit unveils detrimental effects of osteopontin on the blood–brain barrier in acute ischemic stroke
D Spitzer, S Guérit, T Puetz, MI Khel, M Armbrust… - Acta …, 2022 - Springer
Blood–brain barrier (BBB) dysfunction, characterized by degradation of BBB junctional
proteins and increased permeability, is a crucial pathophysiological feature of acute …
proteins and increased permeability, is a crucial pathophysiological feature of acute …
Osteopontin as a candidate of therapeutic application for the acute brain injury
Y Zhou, Y Yao, L Shen, J Zhang… - Journal of cellular …, 2020 - Wiley Online Library
Acute brain injury is the leading cause of human death and disability worldwide, which
includes intracerebral haemorrhage, subarachnoid haemorrhage, cerebral ischaemia …
includes intracerebral haemorrhage, subarachnoid haemorrhage, cerebral ischaemia …
Apoptotic and antimetastatic activities of betulin isolated from Quercus incana against non-small cell lung cancer cells
Background Globally, the prevalence and mortality rates of lung cancer have been
escalated with the increasing trend of tobacco smoking. The toxicity and irresponsive nature …
escalated with the increasing trend of tobacco smoking. The toxicity and irresponsive nature …
Analysis of differentially expressed genes and signaling pathways involved in atherosclerosis and chronic obstructive pulmonary disease
S Kotlyarov - Biomolecular Concepts, 2022 - degruyter.com
Atherosclerosis is an important medical and social problem, and the keys to solving this
problem are still largely unknown. A common situation in real clinical practice is the …
problem are still largely unknown. A common situation in real clinical practice is the …
Potential roles of matricellular proteins in stroke
F Kawakita, H Kanamaru, R Asada, H Suzuki - Experimental Neurology, 2019 - Elsevier
Both ischemic and hemorrhagic strokes are still serious diseases with high mortalities and
morbidities. To improve outcomes of strokes, new therapeutic approaches need to be …
morbidities. To improve outcomes of strokes, new therapeutic approaches need to be …
Glucose-dependent insulinotropic peptide in the high-normal range is associated with increased carotid intima-media thickness
OBJECTIVE While existing evidence supports beneficial cardiovascular effects of glucagon-
like peptide 1 (GLP-1), emerging studies suggest that glucose-dependent insulinotropic …
like peptide 1 (GLP-1), emerging studies suggest that glucose-dependent insulinotropic …
Monocyte transmodulation: the next novel therapeutic approach in overcoming ischemic stroke?
J Park, JY Chang, JY Kim, JE Lee - Frontiers in neurology, 2020 - frontiersin.org
The immune response following neuroinflammation is a vital element of ischemic stroke
pathophysiology. After the onset of ischemic stroke, a specialized vasculature system that …
pathophysiology. After the onset of ischemic stroke, a specialized vasculature system that …