Inflammatory cytokines are necessary for an acute response to injury and the progressive
healing process. However, when this acute response does not resolve and becomes …

Stroke is the second leading cause of death worldwide and has two major subtypes:
ischemic stroke and hemorrhagic stroke. Neuroinflammation is a pathological hallmark of …

Ischemic stroke (IS) is a detrimental neurological disease with limited treatments options. It
has been challenging to define the roles of brain cell subsets in IS onset and progression …

Blood–brain barrier (BBB) dysfunction, characterized by degradation of BBB junctional
proteins and increased permeability, is a crucial pathophysiological feature of acute …

Acute brain injury is the leading cause of human death and disability worldwide, which
includes intracerebral haemorrhage, subarachnoid haemorrhage, cerebral ischaemia …

Background Globally, the prevalence and mortality rates of lung cancer have been
escalated with the increasing trend of tobacco smoking. The toxicity and irresponsive nature …

Atherosclerosis is an important medical and social problem, and the keys to solving this
problem are still largely unknown. A common situation in real clinical practice is the …

Both ischemic and hemorrhagic strokes are still serious diseases with high mortalities and
morbidities. To improve outcomes of strokes, new therapeutic approaches need to be …

OBJECTIVE While existing evidence supports beneficial cardiovascular effects of glucagon-
like peptide 1 (GLP-1), emerging studies suggest that glucose-dependent insulinotropic …

The immune response following neuroinflammation is a vital element of ischemic stroke
pathophysiology. After the onset of ischemic stroke, a specialized vasculature system that …