Pharmacotherapy of neonatal opioid withdrawal syndrome: a review of pharmacokinetics and pharmacodynamics

MW van Hoogdalem, BT McPhail, D Hahn… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction Neonatal opioid withdrawal syndrome (NOWS) often arises in infants born to
mothers who used opioids during pregnancy. Morphine, methadone, and buprenorphine are …

Length of stay among infants with neonatal abstinence syndrome and risk of hospital readmission

H Diop, X Cui, T Nielsen, E Peacock-Chambers… - Maternal and Child …, 2022 - Springer
Objectives To assess whether a shorter length of stay (LOS) is associated with a higher risk
of readmission among newborns with neonatal abstinence syndrome (NAS) and examine …

[HTML][HTML] Placental OPRM1 DNA methylation and associations with neonatal opioid withdrawal syndrome, a pilot study

EM Wachman, A Wang, BC Isley, J Boateng… - Exploration of …, 2020 - ncbi.nlm.nih.gov
Aims: Epigenetic variation of DNA methylation of the mu-opioid receptor gene (OPRM1) has
been identified in the blood and saliva of individuals with opioid use disorder (OUD) and …

Opioid treatment for opioid withdrawal in newborn infants

A Zankl, J Martin, JG Davey… - Cochrane Database of …, 2021 - cochranelibrary.com
Background Neonatal abstinence syndrome (NAS) due to opioid withdrawal may result in
disruption of the mother‐infant relationship, sleep‐wake abnormalities, feeding difficulties …

The MATernaL and Infant NetworK to understand outcomes associated with treatment of opioid use disorder during pregnancy (MAT-LINK): surveillance opportunity

EL Tran, SY Kim, LJ England, C Green… - Journal of Women's …, 2020 - liebertpub.com
Pregnant women with opioid use disorder (OUD) are at risk of overdose, infectious diseases,
and inadequate prenatal care. Additional risks include adverse pregnancy and infant …

Increasing usage of mother's own milk in neonates at risk of neonatal abstinence syndrome: MOM-NAS quality improvement initiative

S Shukla, I Hanna, J Cortez, M Mansour, A Eiges… - Journal of …, 2021 - nature.com
Objective To increase the usage rate of mothers' own milk (MOM) among neonates with
prenatal opioid exposure from a baseline average of 47% to an average of 75% over two …

A cost-effectiveness analysis of rooming-in and breastfeeding in neonatal opioid withdrawal

CM Avram, L Yieh, D Dukhovny… - American journal of …, 2020 - thieme-connect.com
Objective Our cost-effectiveness analysis investigated rooming-in versus not rooming-in to
determine optimal management of neonates with neonatal opioid withdrawal (NOW). Study …

Avoiding NICU transfers for newborns with neonatal opioid withdrawal syndrome (NOWS): a quality improvement initiative to manage NOWS on the mother-baby unit

K Spence, R Boedeker, M Harhausen… - Journal of Addiction …, 2020 - journals.lww.com
Objectives: To reduce transfers to the neonatal intensive care unit (NICU) for neonates with
opioid withdrawal while also reducing length of stay and pharmacologic intervention, and …

Maternal responsivity and oxytocin in opioid‐dependent mothers

KM Daigle, NA Heller, EJ Sulinski… - Developmental …, 2020 - Wiley Online Library
Although prenatal opioid exposure and postnatal withdrawal (neonatal abstinence
syndrome) are associated with infant neurobehavioral deficits, little is known about the …

A Systematic Review of Clinical Practice Guidelines for Neonatal Abstinence Syndrome

Z Wei, Y Gilbert, A Thananjeyan, J Cope, RL Morton… - Children, 2023 - mdpi.com
Background: The prevalence of neonatal abstinence syndrome is increasing, but the
number and quality of clinical practice guidelines available are unknown. This systematic …