[HTML][HTML] Cannabidiol for the treatment of brain disorders: therapeutic potential and routes of administration

GTY Yau, W Tai, JC Arnold, HK Chan… - Pharmaceutical …, 2023 - Springer
The use of cannabidiol (CBD) for treating brain disorders has gained increasing interest.
While the mechanism of action of CBD in these conditions is still under investigation, CBD …

Nanoformulations as a strategy to overcome the delivery limitations of cannabinoids

TS Reddy, R Zomer, N Mantri - Phytotherapy Research, 2023 - Wiley Online Library
Medical cannabis has received significant interest in recent years due to its promising
benefits in the management of pain, anxiety, depression and neurological and movement …

Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses

LC Nguyen, D Yang, V Nicolaescu, TJ Best, H Gula… - Science …, 2022 - science.org
The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ongoing
coronavirus disease 2019 (COVID-19) pandemic underscores the need for new treatments …

[HTML][HTML] Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity

JE LaVigne, R Hecksel, A Keresztes, JM Streicher - Scientific reports, 2021 - nature.com
Limited evidence has suggested that terpenes found in Cannabis sativa are analgesic, and
could produce an “entourage effect” whereby they modulate cannabinoids to result in …

Cannabidiol alleviates perfluorooctanesulfonic acid-induced cardiomyocyte apoptosis by maintaining mitochondrial dynamic balance and energy metabolic …

X Wang, T Xu, D Luo, S Li, X Tang, J Ding… - Journal of agricultural …, 2023 - ACS Publications
Perfluorooctanesulfonic acid (PFOS), a fluorine-containing organic compound, can be
widely detected in the environment and living organisms. Accumulating evidence has shown …

Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling …

C Corpetti, A Del Re, L Seguella, I Palenca… - Phytotherapy …, 2021 - Wiley Online Library
Given the abundancy of angiotensin converting enzyme 2 (ACE‐2) receptors density,
beyond the lung, the intestine is considered as an alternative site of infection and replication …

[HTML][HTML] Development of stable nano-sized transfersomes as a rectal colloid for enhanced delivery of cannabidiol

T Moqejwa, T Marimuthu, PPD Kondiah, YE Choonara - Pharmaceutics, 2022 - mdpi.com
Current cannabidiol (CBD) formulations are challenged with unpredictable release and
absorption. Rational design of a rectal colloid delivery system can provide a practical …

Phase IIb randomized, placebo-controlled, dose-escalating, double-blind study of cannabidiol oil for the relief of symptoms in advanced cancer (MedCan1-CBD)

J Hardy, R Greer, G Huggett, A Kearney… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To determine whether cannabidiol (CBD) oil can improve symptom distress in
patients with advanced cancer receiving palliative care. METHODS Participants were adults …

The emerging role of cannabidiol (CBD) products; a survey exploring the public's use and perceptions of CBD

SK Bhamra, A Desai… - Phytotherapy …, 2021 - Wiley Online Library
The market value of cannabidiol (CBD) is growing as people seek holistic ways of managing
their health. The aim of this study was to explore the public's perceptions and use of CBD …

[HTML][HTML] Medicinal cannabis prescribing in Australia: an analysis of trends over the first five years

SL MacPhail, MA Bedoya-Pérez, R Cohen… - Frontiers in …, 2022 - frontiersin.org
A regulatory framework allowing legal access to medicinal cannabis (MC) products has
operated in Australia since November 2016. MC prescribing by healthcare practitioners …