Background Although post-endoscopic submucosal dissection (ESD) iatrogenic ulcer is
known to heal faster than peptic ulcer, some iatrogenic ulcers show delayed healing. The …

Irritable bowel syndrome (IBS) is a prevalent disease characterized by abdominal pain and
abnormal bowel habits. Pioglitazone is a peroxisome proliferator‐activated receptor (PPAR) …

Abstract Background & Aims: With improved technology, the size of artificial ulcers after
endoscopic submucosal dissection (ESD) has increased. The aim of our study was to …

Wound healing is a complex, highly regulated process and is substantially disrupted by
diabetes. We show here that human wound healing induces specific epigenetic changes …

Hormonal peptides like ghrelin, orexin A (OXA) or nesfatin-1 not only regulate appetite,
which is their basic biological function, but also contribute to mechanisms responsible for …

The objective of this study was to explore the role of apelin in the healing of gastric lesions
induced by stress. Male Wistar rats were exposed to water immersion and restraint stress …

Alarmins exist outside cells and are early warning signals to the immune system; as such,
alarmin receptors are widely distributed on various immune cells. Alarmins, proinflammatory …

Upper gastrointestinal tract integrity is dependent upon the delicate balance between
naturally occurring protective factors as mucus or prostaglandins and damaging factors as …

The present study aimed to show the in vivo mechanisms of action of an indole-thiazolidine
molecule peroxisome-proliferator activated receptor pan-agonist (PPAR pan) and …

Hypoxia can correct the development of diabetes and its complications in animals and
humans, and diabetes exacerbates the gastric ulceration. However, the effect of hypoxia on …