The major function of the skin is to form a barrier between the internal milieu and the hostile
external environment. A permeability barrier that prevents the loss of water and electrolytes …

Skeletal muscle plays an important role in regulating whole-body energy expenditure given
it is a major site for glucose and lipid oxidation. Obesity and type 2 diabetes are causally …

Palmitic acid (PA) is ubiquitously present in dietary fat guaranteeing an average intake of
about 20 g/d. The relative high requirement and relative content in the human body, which …

Since it has been recognized that mitochondria are crucial not only for energy metabolism
but also for other cellular functions, there has been a growing interest in cardiolipin, the …

Triacylglycerol (TAG) synthesis and storage in tissues such as adipose tissue and liver have
important roles in metabolic homeostasis. The molecular identification of genes encoding …

Nonalcoholic fatty liver disease is a major public health burden. Although many features of
nonalcoholic fatty liver disease pathogenesis are known, the specific mechanisms and …

The microbiome plays an important role in lipid metabolism but how the introduction of
probiotic communities affects host lipid metabolism is poorly understood. Using a …

Triacylglycerol (TAG) is the primary unit of energy storage in eukaryotic cells. TAG comprises
more than 90% of the content of white adipocytes, and TAG synthesis is essential in …

The synthesis and storage of neutral lipids in lipid droplets is a fundamental property of
eukaryotic cells, but the spatial organization of this process is poorly understood. Here we …

Human milk TG are a remarkable example of stereo-specific positioning of fatty acids with
structures that are highly conserved and unusual. Not only does human milk contain high …