[HTML][HTML] Metformin: current clinical applications in nondiabetic patients with cancer
K Chen, Y Li, Z Guo, Y Zeng, W Zhang… - Aging (Albany NY …, 2020 - ncbi.nlm.nih.gov
Metformin is one of the most commonly used first-line oral medications for type 2 diabetes
mellitus. Multiple observational studies, reviewed in numerous systematic reviews, have …
mellitus. Multiple observational studies, reviewed in numerous systematic reviews, have …
[HTML][HTML] Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition
MK Crist, B Yaniv, S Palackdharry… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Original research: Metformin increases natural killer cell functions in head and neck squamous
cell carcinoma through CXCL1 inhibition - PMC Back to Top Skip to main content NIH NLM …
cell carcinoma through CXCL1 inhibition - PMC Back to Top Skip to main content NIH NLM …
The impact of metformin on tumor-infiltrated immune cells: preclinical and clinical studies
M Abdelmoneim, MA Aboalela, Y Naoe… - International Journal of …, 2023 - mdpi.com
The tumor microenvironment (TME) plays a pivotal role in the fate of cancer cells, and tumor-
infiltrating immune cells have emerged as key players in shaping this complex milieu …
infiltrating immune cells have emerged as key players in shaping this complex milieu …
Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review
Senescence suppresses tumor growth, while also developing a tumorigenic state in the
nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The …
nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The …
COVID-19. Pandemic surgery guidance
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
Metformin as a therapeutic target in endometrial cancers
TY Lee, UE Martinez-Outschoorn, RJ Schilder… - Frontiers in …, 2018 - frontiersin.org
Endometrial cancer is the most common gynecologic malignancy in developed countries. Its
increasing incidence is thought to be related in part to the rise of metabolic syndrome, which …
increasing incidence is thought to be related in part to the rise of metabolic syndrome, which …
The promising therapeutic effects of metformin on metabolic reprogramming of cancer-associated fibroblasts in solid tumors
S Mostafavi, H Zalpoor, ZM Hassan - Cellular & molecular biology letters, 2022 - Springer
Tumor-infiltrated lymphocytes are exposed to many toxic metabolites and molecules in the
tumor microenvironment (TME) that suppress their anti-tumor activity. Toxic metabolites …
tumor microenvironment (TME) that suppress their anti-tumor activity. Toxic metabolites …
European Laryngological Society position paper on laryngeal dysplasia Part II: diagnosis, treatment, and follow-up
Purpose of review To give an overview of the current knowledge regarding the diagnosis,
treatment, and follow-up of laryngeal dysplasia (LD) and to highlight the contributions of …
treatment, and follow-up of laryngeal dysplasia (LD) and to highlight the contributions of …
MALDI-MSI analysis of cancer drugs: Significance, advances, and applications
Q He, C Sun, J Liu, Y Pan - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Because of the heterogeneity and complexity of tumor structure, cancer drugs often cannot
effectively reach the tumor, which is one of the reasons for drug resistance and treatment …
effectively reach the tumor, which is one of the reasons for drug resistance and treatment …
[HTML][HTML] Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects
R Veeramachaneni, W Yu, JM Newton… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Metformin is a commonly used antidiabetic medication which has demonstrated
promise as an anticancer agent alone and in combination with conventional treatment …
promise as an anticancer agent alone and in combination with conventional treatment …