Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging

ER Quarato, NA Salama, LM Calvi - Current Osteoporosis Reports, 2024 - Springer
Abstract Purpose of the Review In this review, we discuss the most recent scientific
advances on the reciprocal regulatory interactions between the skeletal and hematopoietic …

Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis

Y Zhao, Y Liu, G Zhao, H Lu, Y Liu, C Xue, Z Chang… - Cell reports, 2023 - cell.com
Atherosclerosis, a leading health concern, stems from the dynamic involvement of immune
cells in vascular plaques. Despite its significance, the interplay between chromatin …

Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function

M Pfefferlé, F Vallelian - Transcription factors in blood cell development, 2024 - Springer
Abstract NFE2-related factor 2 (NRF2) is a master transcription factor (TF) that coordinates
key cellular homeostatic processes including antioxidative responses, autophagy …

NRF1 or NRF2: Emerging role of redox homeostasis on PERK/NRF/autophagy mediated antioxidant in tumor and patient dependent chemo sensitivity

S Dastghaib, SM Shafiee, F Ramezani, N Ashtari… - 2024 - preprints.org
Chemo-resistance is a substantial challenge in the realm of cancer treatment that requires
exploring new therapeutic approaches for effective mitigation. Achieving this goal requires …

ARID1A-loss in cancer causes R-loop mediated genome instability and sensitizes cells to KEAP1 perturbation

LA Fournier - 2023 - open.library.ubc.ca
Mutations in ARID1A, the DNA-binding subunit of the BAF chromatin remodeling complex,
occur in about 7% of all cancers. Loss of ARID1A in cancer results in the dysregulation of …

Check for Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function Marc Pfefferlé and Florence Vallelian

M Pfefferlé - Transcription factors in blood cell development - books.google.com
NFE2-related factor 2 (NRF2) is a master transcription factor (TF) that coordinates key
cellular homeostatic processes including antioxidative responses, autophagy, proteostasis …