Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Spotlight on therapeutic efficiency of mesenchymal stem cells in viral infections with a focus on COVID-19

S Yasamineh, HG Kalajahi, P Yasamineh… - Stem Cell Research & …, 2022 - Springer
The SARS-COV-2 virus has infected the world at a very high rate by causing COVID-19
disease. Nearly 507 million individuals have been infected with this virus, with …

COVID-DSNet: A novel deep convolutional neural network for detection of coronavirus (SARS-CoV-2) cases from CT and Chest X-Ray images

HC Reis, V Turk - Artificial Intelligence in Medicine, 2022 - Elsevier
Abstract COVID-19 (SARS-CoV-2), which causes acute respiratory syndrome, is a
contagious and deadly disease that has devastating effects on society and human life …

A systematic review on the modifications of extracellular vesicles: a revolutionized tool of nano-biotechnology

A Raghav, GB Jeong - Journal of Nanobiotechnology, 2021 - Springer
Abstract Background Tailoring extracellular vesicles (EVs) can bequeath them with diverse
functions and efficient performance in nano-biotechnology. Engineering and modification of …

Cigarette smoke-induced respiratory response: insights into cellular processes and biomarkers

SR Cha, J Jang, SM Park, SM Ryu, SJ Cho, SR Yang - Antioxidants, 2023 - mdpi.com
Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …

Extracellular vesicles in neurodegenerative diseases: A systematic review

A Raghav, M Singh, GB Jeong, R Giri… - Frontiers in molecular …, 2022 - frontiersin.org
Introduction Extracellular vesicles (EVs) are known to have a significant role in the central
nervous system (CNS) and neurodegenerative disease. Methods PubMed, Scopus, ISI Web …

Therapeutic role of mesenchymal stem cell-derived exosomes in respiratory disease

MJ Zargar, S Kaviani, M Vasei… - Stem Cell Research & …, 2022 - Springer
Exosomes are extracellular vesicles found in various tissues, blood circulation, and tissue
fluids, secreted into the extracellular environment by fusing a multivesicular body with a …

Tagged extracellular vesicles with the RBD of the viral spike protein for delivery of antiviral agents against SARS-COV-2 infection

Y Fu, S Xiong - Journal of Controlled Release, 2021 - Elsevier
The worldwide spread of COVID-19 highlights the urgent need for an efficient approach to
rapidly develop therapeutics and prophylactics against SARS-CoV-2. Extracellular vesicle …

Exosomes as natural nanocarriers for RNA-based therapy and prophylaxis

A Gorshkov, L Purvinsh, A Brodskaia, A Vasin - Nanomaterials, 2022 - mdpi.com
Exosomes are natural nanocontainers actively secreted by the body's cells and transmitting
molecular signals of various types to recipient cells. Cellular mechanisms of exosomes' …

Microfluidic tools for enhanced characterization of therapeutic stem cells and prediction of their potential antimicrobial secretome

P Marrazzo, V Pizzuti, S Zia, A Sargenti, D Gazzola… - Antibiotics, 2021 - mdpi.com
Antibiotic resistance is creating enormous attention on the development of new antibiotic-
free therapy strategies for bacterial diseases. Mesenchymal stromal stem cells (MSCs) are …