COVID-19 inflammation and implications in drug delivery

M Zoulikha, F Huang, Z Wu, W He - Journal of Controlled Release, 2022 - Elsevier
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …

Role of mesenchymal stem cells and extracellular vesicles in idiopathic pulmonary fibrosis

S Kletukhina, G Mutallapova, A Titova… - International Journal of …, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial fibrotic disease that leads to
disability and death within 5 years of diagnosis. Pulmonary fibrosis is a disease with a …

Mesenchymal stromal cell-derived tailored exosomes treat bacteria-associated diabetes foot ulcers: a customized approach from bench to bed

A Raghav, P Tripathi, BK Mishra, GB Jeong… - Frontiers in …, 2021 - frontiersin.org
Exosomes are nano-vesicles of endosomal origin inherited with characteristics of drug
delivery and cargo loading. Exosomes offer a diverse range of opportunities that can be …

Immunopathology and immunosenescence, the immunological key words of severe COVID-19. Is there a role for stem cell transplantation?

ME Ligotti, F Pojero, G Accardi, A Aiello… - Frontiers in Cell and …, 2021 - frontiersin.org
The outcomes of Coronavirus disease-2019 (COVID-19) vary depending on the age, health
status and sex of an individual, ranging from asymptomatic to lethal. From an immunologic …

Potential cell-based and cell-free therapy for patients with COVID-19

MI Tan, NM Alfarafisa, P Septiani, A Barlian… - Cells, 2022 - mdpi.com
Since it was first reported, the novel coronavirus disease 2019 (COVID-19) remains an
unresolved puzzle for biomedical researchers in different fields. Various treatments, drugs …

Molecular mechanisms of multi-organ failure in COVID-19 and potential of stem cell therapy

A Bhalerao, S Raut, B Noorani, S Mancuso, L Cucullo - Cells, 2021 - mdpi.com
As the number of confirmed cases and deaths occurring from Coronavirus disease 2019
(COVID-19) surges worldwide, health experts are striving hard to fully comprehend the …

Unveiling the promise: Exosomes as game‐changers in anti‐infective therapy

VP Chavda, G Luo, R Bezbaruah, T Kalita… - …, 2024 - Wiley Online Library
Extracellular vesicles (EVs)‐based intercellular communication (through exosomes,
microvesicles, and apoptotic bodies) is conserved across all kingdoms of life. In recent …

Engineered extracellular vesicles in treatment of type 1 diabetes mellitus: a prospective review

A Raghav, H Ashraf, GB Jeong - Biomedicines, 2022 - mdpi.com
Insulin replacement is an available treatment for autoimmune type 1 diabetes mellitus
(T1DM). There are multiple limitations in the treatment of autoimmune diseases such as …

Promising use of immune cell‐derived exosomes in the treatment of SARS‐CoV‐2 infections

M Alahdal, E Elkord - Clinical and translational medicine, 2022 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is persistently
threatening the lives of thousands of individuals globally. It triggers pulmonary oedema …

Mesenchymal Stem-Cell Derived Exosome Therapy as a Potential Future Approach for Treatment of Male Infertility Caused by Chlamydia Infection

M Izadi, L Dehghan Marvast, ME Rezvani… - Frontiers in …, 2022 - frontiersin.org
Some microbial sexually transmitted infections (STIs) have adverse effects on the
reproductive tract, sperm function, and male fertility. Given that STIs are often asymptomatic …