Human tyrosinase (hs TYR) is the key enzyme ensuring the conversion of l-tyrosine to
dopaquinone, thereby initiating melanin synthesis, ie, melanogenesis. Although the protein …

Skin lightening for cosmetic reasons is associated with profound negative impacts on well-
being, and adverse effects on the skin, resulting in immense challenges for dermatologists …

The Montreal Protocol has limited increases in the UV-B (280–315 nm) radiation reaching
the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the …

Background: The Minamata Convention on Mercury (Article 4) prohibits the manufacture,
import, or export of skin-lightening products containing mercury concentrations above 1 …

Polygenic scores offer developmental psychologists new methods for integrating genetic
information into research on how people change and develop across the life span. Indeed …

Cosmetic skin lightening is a growing dermatologic public health problem that affects
communities of color worldwide. Despite well-documented adverse health effects, cosmetic …

Background There is an urgent need to address the safety problems caused by the use of
skin lightening cosmetics. Evidence suggests that some of them may contain heavy metals …

Background Skin-lightening (SL) products are common, especially in Africa. Adverse effects
from these products represent a public health concern. Use of these products in Somaliland …

The indiscriminate use of non-regulated skin lighteners among African populations has
raised health concerns due to the negative effects associated with skin lightener toxicity. For …

Importance Asian American individuals are the fastest growing racial group in the US but
remain underrepresented in health disparities research, including research on skin cancer …