Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …

Dermatophytoses (ringworms) are among the most frequent skin infections and are a highly
prevalent cause of human disease worldwide. Despite the incidence of these superficial …

Clearance of invading microbes requires phagocytes of the innate immune system.
However, successful pathogens have evolved sophisticated strategies to evade immune …

Vulvovaginal candidiasis (VVC) is a symptomatic inflammation of the vagina mainly caused
by C. albicans. Other species, such as C. parapsilosis, C. glabrata, C. tropicalis, and C …

Fungal pathogens can rarely cause diseases in immunocompetent individuals. However,
commensal and normally nonpathogenic environmental fungi can cause life-threatening …

Of all the pathogen recognition receptor families, C-type lectin receptor (CLR)-induced
intracellular signal cascades are indispensable for the initiation and regulation of antifungal …

The dimorphic fungus Candida albicans is both a harmless commensal organism on
mucosal surfaces and an opportunistic pathogen. Under certain predisposing conditions, the …

Purpose: Fungal keratitis is a sight-threatening corneal infection caused by fungal
pathogens, and the pathogenic mechanisms have not been fully elucidated. The aim of this …

The innate immune system is the first line of defense against invasive fungal infections. As a
consequence, many successful fungal pathogens have evolved elegant strategies to interact …

Post-translational modifications (PTMs) change the structure and function of proteins and
regulate a diverse array of biological processes. Fungal pathogens rely on PTMs to …