[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer

T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

Effects and mechanisms of curcumin for the prevention and management of cancers: An updated review

ZJ Yang, SY Huang, DD Zhou, RG Xiong, CN Zhao… - Antioxidants, 2022 - mdpi.com
Cancer is the leading cause of death in the world. Curcumin is the main ingredient in
turmeric (Curcuma longa L.), and is widely used in the food industry. It shows anticancer …

The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions

A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …

Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects

Y Hussain, L Islam, H Khan, R Filosa… - Phytotherapy …, 2021 - Wiley Online Library
The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

Versatile role of curcumin and its derivatives in lung cancer therapy

M Ashrafizadeh, M Najafi, P Makvandi… - Journal of cellular …, 2020 - Wiley Online Library
Lung cancer is a main cause of death all over the world with a high incidence rate.
Metastasis into neighboring and distant tissues as well as resistance of cancer cells to …

Synucleins: new data on misfolding, aggregation and role in diseases

A Surguchov, A Surguchev - Biomedicines, 2022 - mdpi.com
The synucleins are a family of natively unfolded (or intrinsically unstructured) proteins
consisting of α-, β-, and γ-synuclein involved in neurodegenerative diseases and cancer …

Current insights into epigenetics, noncoding RNA interactome and clinical pharmacokinetics of dietary polyphenols in cancer chemoprevention

D Shah, M Gandhi, A Kumar… - Critical reviews in …, 2023 - Taylor & Francis
Several studies have reported the health-beneficial effects of dietary phytochemicals,
namely polyphenols, to prevent various diseases, including cancer. Polyphenols, like (−) …

Curcumin from turmeric rhizome: A potential modulator of DNA methylation machinery in breast cancer inhibition

K Fabianowska-Majewska, A Kaufman-Szymczyk… - Nutrients, 2021 - mdpi.com
One of the most systematically studied bioactive nutraceuticals for its benefits in the
management of various diseases is the turmeric-derived compounds: curcumin. Turmeric …

Curcumin encapsulation in nanostructures for cancer therapy: A 10-year overview

NA D'Angelo, MA Noronha, IS Kurnik… - International journal of …, 2021 - Elsevier
Curcumin (CUR) is a phenolic compound present in some herbs, including Curcuma longa
Linn.(turmeric rhizome), with a high bioactive capacity and characteristic yellow color. It is …

Potential roles and molecular mechanisms of bioactive ingredients in Curcumae Rhizoma against breast cancer

P Zhao, J Qiu, C Pan, Y Tang, M Chen, H Song, J Yang… - Phytomedicine, 2023 - Elsevier
Background Breast cancer is the most prevalent cancer worldwide, with high morbidity and
mortality. Despite great advances in the therapeutic strategies, the survival rate in the past …