Left ventricular hypertrophy is a leading risk factor for cardiovascular morbidity and mortality.
Although reverse ventricular remodelling was long thought to be irreversible, evidence from …

Mitochondria are the source of cellular energy production and are present in different types
of cells. However, their function is especially important for the heart due to the high demands …

The global burden of hypertension is rising and accounts for substantial morbidity and
mortality. Lifestyle factors such as diet and physical inactivity contribute to this burden …

Cardiac stress can induce morphological, structural and functional changes of the heart,
referred to as cardiac remodeling. Myocardial infarction or sustained overload as a result of …

The heart must continuously pump blood to supply the body with oxygen and nutrients. To
maintain the high energy consumption required by this role, the heart is equipped with …

The heart is capable of responding to stressful situations by increasing muscle mass, which
is broadly defined as cardiac hypertrophy. This phenomenon minimizes ventricular wall …

Cardiovascular disease is the number one cause of mortality in the Western world. The heart
responds to many cardiopathological conditions with hypertrophic growth by enlarging …

miRNAs are small non-coding RNAs (ncRNAs), which regulate gene expression. Here, the
authors describe the contribution of miRNAs to cardiac biology and disease. They discuss …

Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause
mortality, with increases in cardiorespiratory fitness associated with corresponding …

Limited microRNAs (miRNAs, miRs) have been reported to be necessary for exercise-
induced cardiac growth and essential for protection against pathological cardiac …