SOD1 in neurotoxicity and its controversial roles in SOD1 mutation-negative ALS

Y Hayashi, K Homma, H Ichijo - Advances in biological regulation, 2016 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a serious neurodegenerative disorder that is
characterized by the selective death of motor neurons. While the fundamental cause of the …

Sleep disturbances in patients with amyotrophic lateral sclerosis: current perspectives

M Boentert - Nature and science of sleep, 2019 - Taylor & Francis
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease inevitably leading
to generalized muscle weakness and premature death. Sleep disturbances are extremely …

Attention and P300-based BCI performance in people with amyotrophic lateral sclerosis

A Riccio, L Simione, F Schettini, A Pizzimenti… - Frontiers in human …, 2013 - frontiersin.org
The purpose of this study was to investigate the support of attentional and memory
processes in controlling a P300-based brain-computer interface (BCI) in people with …

[HTML][HTML] Effects of exercise on sleep in neurodegenerative disease

AA Memon, JJ Coleman, AW Amara - Neurobiology of disease, 2020 - Elsevier
As the population ages, the incidence and prevalence of neurodegenerative disorders will
continue to increase. Persons with neurodegenerative disease frequently experience sleep …

Amyotrophic lateral sclerosis: new perpectives and update

M Orsini, AB Oliveira, OJM Nascimento… - Neurology …, 2015 - mdpi.com
Amyotrophic lateral sclerosis (ALS), Charcot's disease or Lou Gehrig's disease, is a term
used to cover the spetrum of syndromes caracterized by progressive degeneration of motor …

The natural history of motor neuron disease: assessing the impact of specialist care

T Aridegbe, R Kandler, SJ Walters… - … Lateral Sclerosis and …, 2013 - Taylor & Francis
Many centres in the UK care for patients with motor neuron disease (MND) in a
multidisciplinary clinic (MDC). It has been demonstrated that such care results in better …

Do-not-resuscitate order: a view throughout the world

C Santonocito, G Ristagno, A Gullo, MH Weil - Journal of Critical Care, 2013 - Elsevier
Resuscitation has the ability to reverse premature death. It can also prolong terminal illness,
increase discomfort, and consume resources. The do-not-resuscitate (DNR) order and …

[HTML][HTML] A benchmark for hypothalamus segmentation on T1-weighted MR images

L Rodrigues, TJR Rezende, G Wertheimer, Y Santos… - NeuroImage, 2022 - Elsevier
The hypothalamus is a small brain structure that plays essential roles in sleep regulation,
body temperature control, and metabolic homeostasis. Hypothalamic structural …

A metadata analysis of oxidative stress etiology in preclinical amyotrophic lateral sclerosis: benefits of antioxidant therapy

L Bond, K Bernhardt, P Madria, K Sorrentino… - Frontiers in …, 2018 - frontiersin.org
Oxidative stress, induced by an imbalance of free radicals, incites neurodegeneration in
Amyotrophic Lateral Sclerosis (ALS). In fact, a mutation in antioxidant enzyme superoxide …

Atypical motor neuron disease variants: still a diagnostic challenge in neurology

W Pinto, R Debona, PP Nunes, ACD Assis… - Revue …, 2019 - Elsevier
Motor neuron disease (MND) represents a wide and heterogeneous expanding group of
disorders involving the upper or lower motor neurons, mainly represented by amyotrophic …