miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

[HTML][HTML] miRNAs and lncRNAs as novel therapeutic targets to improve cancer immunotherapy

MT Di Martino, C Riillo, F Scionti, K Grillone, N Polerà… - Cancers, 2021 - mdpi.com
Simple Summary Cancer onset and progression are promoted by high deregulation of the
immune system. Recently, major advances in molecular and clinical cancer immunology …

[HTML][HTML] Ratiometric fluorescence detection of colorectal cancer-associated exosomal miR-92a-3p with DSN-assisted signal amplification by a MWCNTs@ Au NCs …

Z Sun, J Li, Y Tong, L Zhao, X Zhou, H Li, C Wang… - Biosensors, 2022 - mdpi.com
The detection of miRNA shows great promise in disease diagnosis. In this work, a ratiometric
fluorescent biosensor based on multi-walled carbon nanotubes@ gold nanoclusters …

[HTML][HTML] The impact of lncRNAs and miRNAs on apoptosis in lung cancer

S Ghafouri-Fard, A Aghabalazade, H Shoorei… - Frontiers in …, 2021 - frontiersin.org
Apoptosis is a coordinated cellular process that occurs in several physiological situations.
Dysregulation of apoptosis has been documented in numerous pathological situations …

Cannabinoid-induced changes in the immune system: The role of microRNAs

HK Bhatt, D Song, G Musgrave, PSS Rao - International …, 2021 - Elsevier
Naturally occurring cannabinoids have been used by humans for their medicinal benefits for
over several millennia. While the use of cannabinoids has been strictly regulated in the past …

Vitamins A and D Enhance the Expression of Ror-γ-Targeting miRNAs in a Mouse Model of Multiple Sclerosis

M Mohammadi-Kordkhayli, MA Sahraian… - Molecular …, 2023 - Springer
Autoreactive T cells, particularly those characterized by a Th17 phenotype, exert significant
influence on the pathogenesis of multiple sclerosis (MS). The present study aimed to …

Post-transcriptional control of T-cell development in the thymus

A Krueger, M Łyszkiewicz, V Heissmeyer - Immunology Letters, 2022 - Elsevier
T-cell development in the thymus is dependent on the continual colonization by bone-
marrow derived progenitor cells. Once inside the thymus, progenitors undergo a series of …

Oligonucleotide therapeutics and their chemical modification strategies for clinical applications

H Kim, S Kim, D Lee, D Lee, J Yoon, H Lee - Journal of Pharmaceutical …, 2024 - Springer
Background Oligonucleotide therapeutics have emerged as a promising and dynamic class
of pharmaceutical agents with remarkable potential for treating a wide spectrum of genetic …

[HTML][HTML] Involvement of TAL1-microRNA Axis in the Progression of T-cell Acute Lymphoblastic Leukemia

D Purrahman, H Yousefi, A Shojaeian… - Gene …, 2024 - xiahepublishing.com
The T-cell acute lymphoblastic leukemia 1 (TAL-1) transcription factor is crucial for T-cell
differentiation, but the ectopic expression in 30% of cases can disrupt normal differentiation …

Вплив miR-155 грудного молока на стан здоров'я недоношених новонароджених

ОЄ Абатуров, АО Товарницька - Здоров'я дитини= Zdorov'e …, 2022 - repo.dma.dp.ua
Грудне молоко (ГМ)—важливе джерело мікроРНК (miR). МікроРНК мають високу
стійкість до впливу ферментів шлунково-кишкового тракту і добре всмоктуються в …