Basis of virulence in enterotoxin-mediated staphylococcal food poisoning
EL Fisher, M Otto, GYC Cheung - Frontiers in microbiology, 2018 - frontiersin.org
The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that
share structural and functional similarities and possess potent superantigenic activity …
share structural and functional similarities and possess potent superantigenic activity …
Superantigen recognition and interactions: functions, mechanisms and applications
AM Deacy, SKE Gan, JP Derrick - Frontiers in Immunology, 2021 - frontiersin.org
Superantigens are unconventional antigens which recognise immune receptors outside
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …
their usual recognition sites eg complementary determining regions (CDRs), to elicit a …
[HTML][HTML] Update on targeted cancer therapies, single or in combination, and their fine tuning for precision medicine
SS Bashraheel, A Domling, SK Goda - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Background Until recently, patients who have the same type and stage of cancer all receive
the same treatment. It has been established, however, that individuals with the same …
the same treatment. It has been established, however, that individuals with the same …
Staphylococcal superantigens: pyrogenic toxins induce toxic shock
T Krakauer - Toxins, 2019 - mdpi.com
Staphylococcal enterotoxin B (SEB) and related superantigenic toxins produced by
Staphylococcus aureus are potent activators of the immune system. These protein toxins …
Staphylococcus aureus are potent activators of the immune system. These protein toxins …
The immune system of HIV-exposed uninfected infants
Infants born to human immunodeficiency virus (HIV) infected women are HIV-exposed but
the majority remains uninfected [ie, HIV-exposed uninfected (HEU)]. HEU infants suffer …
the majority remains uninfected [ie, HIV-exposed uninfected (HEU)]. HEU infants suffer …
DEBS–a unification theory for dry eye and blepharitis
JM Rynerson, HD Perry - Clinical Ophthalmology, 2016 - Taylor & Francis
For many years, blepharitis and dry eye disease have been thought to be two distinct
diseases, and evaporative dry eye distinct from aqueous insufficiency. In this treatise, we …
diseases, and evaporative dry eye distinct from aqueous insufficiency. In this treatise, we …
Hazard of staphylococcal enterotoxins in food and promising strategies for natural products against virulence
C Liu, Y Shen, M Yang, K Chi… - Journal of agricultural and …, 2022 - ACS Publications
Staphylococcal enterotoxins (SEs) secreted by Staphylococcus aureus frequently
contaminate food and cause serious foodborne diseases but are ignored during food …
contaminate food and cause serious foodborne diseases but are ignored during food …
Virulence factor targeting of the bacterial pathogen Staphylococcus aureus for vaccine and therapeutics
TL Kane, KE Carothers, SW Lee - Current drug targets, 2018 - ingentaconnect.com
Background: Staphylococcus aureus is a major bacterial pathogen capable of causing a
range of infections in humans from gastrointestinal disease, skin and soft tissue infections, to …
range of infections in humans from gastrointestinal disease, skin and soft tissue infections, to …
CC-99677, a novel, oral, selective covalent MK2 inhibitor, sustainably reduces pro-inflammatory cytokine production
R Gaur, KA Mensah, J Stricker, M Adams… - Arthritis Research & …, 2022 - Springer
Background Mitogen-activated protein kinase (MAPK)-activated protein kinase-2 (MK2) is
activated downstream of p38 MAPK and regulates stability of mRNAs encoding inflammatory …
activated downstream of p38 MAPK and regulates stability of mRNAs encoding inflammatory …
Staphylococcal enterotoxin B-induced microRNA-155 targets SOCS1 to promote acute inflammatory lung injury
R Rao, P Nagarkatti, M Nagarkatti - Infection and immunity, 2014 - Am Soc Microbiol
Staphylococcal enterotoxin B (SEB) causes food poisoning in humans. It is considered a
biological weapon, and inhalation can trigger lung injury and sometimes respiratory failure …
biological weapon, and inhalation can trigger lung injury and sometimes respiratory failure …