A form of dementia distinct from healthy cognitive aging, Alzheimer's disease (AD) is a
complex multi-stage disease that currently afflicts over 50 million people worldwide …

Alzheimer's disease (AD) is one of the progressive neurodegenerative disorders and the
most common cause of dementia in the elderly worldwide causing difficulties in the daily life …

Transgenic models are useful tools for studying the pathogenesis of and drug development
for Alzheimer's Disease (AD). AD models are constructed usually using overexpression or …

Lipids play crucial roles in the susceptibility and brain cellular responses to Alzheimer's
disease (AD) and are increasingly considered potential soluble biomarkers in cerebrospinal …

Animal models of Alzheimer's disease amyloidosis that recapitulate cerebral amyloid-beta
pathology have been widely used in preclinical research and have greatly enabled the …

Accumulation of amyloid-β peptide (Aβ) aggregates in synapses may contribute to the
profound synaptic loss characteristic of Alzheimer9s disease (AD). The origin of synaptic Aβ …

How biomedical research using various animal species and in vitro cellular systems has
resulted in both major successes and translational failure. In Model Systems in Biology …

The pathogenesis of Alzheimer's disease (AD) is highly complex and multifactorial.
Compared with Aβ, the pathological changes associated with tau are more related to the …

As the understanding of immune responses in Alzheimer's disease (AD) is in its early
phases, there remains an urgency to identify the cellular and molecular processes driving …

In the current study, for the first time, we study mitophagy enhancer urolithin A and a
combination of urolithin A+ green tea extract EGCG against human Aβ peptide-induced …