Atherosclerotic cardiovascular (CV) disease (ASCVD) incidence and mortality rates are
declining in many countries in Europe, but it is still a major cause of morbidity and mortality …

for digital applications (smartphones, etc.). These versions are abridged and thus, for more
detailed information, the user should always access to the full text version of the guidelines …

Background Whether acetazolamide, a carbonic anhydrase inhibitor that reduces proximal
tubular sodium reabsorption, can improve the efficiency of loop diuretics, potentially leading …

ESC and updated. The Task Force received its entire financial support from the ESC without
any involvement from the healthcare industry. The ESC CPG supervises and coordinates the …

4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

Background SGLT2 inhibitors are strongly recommended in guidelines to treat patients with
heart failure with reduced ejection fraction, but their clinical benefits at higher ejection …

Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection
fraction (EF) and the condition is termed heart failure with preserved ejection fraction …

Background Data from a 5-year follow-up of outcomes after transcatheter edge-to-edge
repair of severe mitral regurgitation, as compared with outcomes after maximal doses of …

Objectives This report describes the baseline clinical profiles and management of DELIVER
(Dapagliflozin Evaluation to Improve the Lives of Patients With Preserved Ejection Fraction …

Importance Cardiogenic shock affects between 40 000 and 50 000 people in the US per
year and is the leading cause of in-hospital mortality following acute myocardial infarction …