Chronic myeloid leukemia (CML) is one of the most common leukemias occurring in the
adult population. The course of CML is divided into three phases: the chronic phase, the …

The JNKs are members of mitogen-activated protein kinases (MAPK) which regulate many
physiological processes including inflammatory responses, macrophages, cell proliferation …

The bone marrow aspiration procedure is used in hematological diseases and consists of a
painful, invasive procedure causing anxiety‐associated symptoms. The present study …

Medication-induced pulmonary injury (MIPI) is a complex medical condition that has become
increasingly common yet remains stubbornly difficult to diagnose. Diagnosis can be aided …

Abstract Chronic Myeloid Leukemia (CML) is characterized by chromosomal aberrations
involving the fusion of the BCR and ABL genes on chromosome 22, resulting from a …

OBJECTIVE: To investigate the inhibitory effects of dasatinib on proliferation, function, and
signaling events on CD8+ T cells. MATERIALS AND METHODS: Carboxyfluorescein …

Our understanding of cancer metabolism spans from its role in cellular energetics and
supplying the building blocks necessary for proliferation, to maintaining cellular redox and …

Abstract Imatinib, nilotinib, dasatinib, bosutinib, ponatinib, and asciminib are FDA-approved
tyrosine kinase inhibitors (TKIs) for chronic myeloid leukemia (CML), each of which has a …

Purpose To investigate the experiences of adults living with chronic myeloid leukaemia and
treated with tyrosine kinase inhibitors, with particular reference to factors influencing …

Background: Chronic Myeloid Leukaemia (CML) starts in certain blood-forming cells of the
bone marrow when cells acquire Philadelphia chromosome. Nowadays, scientists attempt to …