[HTML][HTML] Iron–sulfur clusters as inhibitors and catalysts of viral replication
K Honarmand Ebrahimi, S Ciofi-Baffoni… - Nature Chemistry, 2022 - nature.com
A virus hijacks host cellular machineries and metabolites in order to reproduce. In response,
the innate immune system activates different processes to fight back. Although many aspects …
the innate immune system activates different processes to fight back. Although many aspects …
Network for network concept offers new insights into host-SARS-CoV-2 protein interactions and potential novel targets for developing antiviral drugs
Abstract SARS-CoV-2, the causal agent of COVID-19, is primarily a pulmonary virus that can
directly or indirectly infect several organs. Despite many studies carried out during the …
directly or indirectly infect several organs. Despite many studies carried out during the …
[HTML][HTML] Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor
O Danziger, RS Patel, EJ DeGrace, MR Rosen… - PLoS …, 2022 - journals.plos.org
Interferons establish an antiviral state through the induction of hundreds of interferon-
stimulated genes (ISGs). The mechanisms and viral specificities for most ISGs remain …
stimulated genes (ISGs). The mechanisms and viral specificities for most ISGs remain …
[HTML][HTML] Interactome analysis of the nucleocapsid protein of SARS-CoV-2 virus
X Zheng, Z Sun, L Yu, D Shi, M Zhu, H Yao, L Li - Pathogens, 2021 - mdpi.com
SARS-CoV-2 infection has caused a global pandemic that has severely damaged both
public health and the economy. The nucleocapsid protein of SARS-CoV-2 is multifunctional …
public health and the economy. The nucleocapsid protein of SARS-CoV-2 is multifunctional …
Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection
SUMMARY SARS-CoV-2 can cause a range of symptoms in infected individuals, from mild
respiratory illness to acute respiratory distress syndrome. A systematic understanding of the …
respiratory illness to acute respiratory distress syndrome. A systematic understanding of the …
[HTML][HTML] Potential molecular mechanisms of rare anti-tumor immune response by SARS-CoV-2 in isolated cases of lymphomas
Recently, two cases of complete remission of classical Hodgkin lymphoma (cHL) and
follicular lymphoma (FL) after SARS-CoV-2 infection were reported. However, the precise …
follicular lymphoma (FL) after SARS-CoV-2 infection were reported. However, the precise …
[HTML][HTML] Transcriptional profiles analysis of COVID-19 and malaria patients reveals potential biomarkers in children
N Lambert, JA Kengne-Ouafo, WM Rissy, U Diane… - BioRxiv, 2022 - ncbi.nlm.nih.gov
The clinical presentation overlap between malaria and COVID-19 poses special challenges
for rapid diagnosis in febrile children. In this study, we collected RNA-seq data of children …
for rapid diagnosis in febrile children. In this study, we collected RNA-seq data of children …
Integrative multi-omics landscape of non-structural protein 3 of severe acute respiratory syndrome coronaviruses
Abstract The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection is currently a global pandemic. Extensive …
syndrome coronavirus 2 (SARS-CoV-2) infection is currently a global pandemic. Extensive …
Multifaceted roles of TAX1BP1 in autophagy
ABSTRACT TAX1BP1 is a selective macroautophagy/autophagy receptor that plays a
central role in host defense to pathogens and in regulating the innate immune system …
central role in host defense to pathogens and in regulating the innate immune system …
[HTML][HTML] COVIDrugNet: a network-based web tool to investigate the drugs currently in clinical trial to contrast COVID-19
L Menestrina, C Cabrelle, M Recanatini - Scientific Reports, 2021 - nature.com
The COVID-19 pandemic poses a huge problem of public health that requires the
implementation of all available means to contrast it, and drugs are one of them. In this …
implementation of all available means to contrast it, and drugs are one of them. In this …