Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Cell-cell interactions and cell adhesion are key mediators of cancer progression and
facilitate hallmarks of cancer including immune evasion and metastatic dissemination. Many …

The endothelial cell adhesion molecule E-selectin is a key component of the bone marrow
hematopoietic stem cell (HSC) vascular niche regulating balance between HSC self …

PD-L1, frequently expressed in human cancers, engages with PD-1 on immune cells and
contributes to cancer immune evasion. As such, antibodies blocking the PD-1/PD-L1 …

Simple Summary Sialylation is a post-translational modification that consists in the addition
of sialic acid to growing glycan chains on glycoproteins and glycolipids. Aberrant sialylation …

As a classical hybrid dye, coumarin-hemicyanine dye has been widely utilized as a
remarkably powerful fluorescent imaging tool in the fields of reactive species detection …

Alteration of glycosylation, a hallmark of cancer, results in the production of tumor-
associated glycans or glycoproteins. These molecules are subsequently secreted or …

Glycosidases are ubiquitous enzymes that catalyze the hydrolysis of glycosidic linkages in
oligosaccharides and glycoconjugates. These enzymes play a vital role in a wide variety of …

Studies have shown that the presence of tumor infiltrating lymphocytes (TILs) in Triple
Negative Breast Cancer (TNBC) is associated with better prognosis. However, the molecular …

Inter-tumor heterogeneity is a result of genomic, transcriptional, translational, and post-
translational molecular features. To investigate the roles of protein glycosylation in the …