Physical activity decreases the risk of a network of diseases, and exercise may be
prescribed as medicine for lifestyle-related disorders such as type 2 diabetes, dementia …

Regular exercise reduces the risk of chronic metabolic and cardiorespiratory diseases, in
part because exercise exerts anti-inflammatory effects. However, these effects are also likely …

Epidemiological studies demonstrate an association between breast cancer (BC) and
systemic dysregulation of glucose metabolism. However, how BC influences glucose …

Metformin, an insulin-lowering agent, has been associated with decreased cancer risk in
epidemiologic studies in diabetic patients. We performed a comprehensive literature search …

In the past, the role of physical activity as a life-style modulating factor has been considered
as that of a tool to balance energy intake. Although it is important to avoid obesity, physical …

Background A growing body of evidence has suggested that metformin potentially reduces
the risk of cancer. Our objective was to enhance the precision of estimates of the effect of …

Skeletal muscle is the largest organ in the body. Skeletal muscles are primarily
characterized by their mechanical activity required for posture, movement, and breathing …

Type 2 diabetes, cardiovascular diseases, colon cancer, breast cancer, dementia and
depression constitute a cluster of diseases, which defines 'a diseasome of physical …

Purpose Population studies have suggested that metformin use in diabetic patients
decreases cancer incidence and mortality. Metformin inhibits the growth of cancer cells in …

Physical inactivity has recently been identified as a major and independent risk factor for the
development of dementia and cognitive decline. In addition to the effect of exercise with …