Mesenchymal stem cells for neurological disorders

A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …

[HTML][HTML] Mesenchymal stromal cells and exosomes: progress and challenges

MH Forsberg, JA Kink, P Hematti… - Frontiers in cell and …, 2020 - frontiersin.org
Due to their robust immunomodulatory capabilities, mesenchymal stem/stromal cells (MSCs)
have been used as a cellular therapy for a number of human diseases. Part of the …

Alpha‐synuclein oligomers and neurofilament light chain in spinal fluid differentiate multiple system atrophy from Lewy body synucleinopathies

W Singer, AM Schmeichel, M Shahnawaz… - Annals of …, 2020 - Wiley Online Library
Objective To explore the role of alpha‐synuclein (αSyn) oligomers and neurofilament light
chain (NFL) in cerebrospinal fluid (CSF) as markers of early multiple system atrophy (MSA) …

[HTML][HTML] Clinical utility of mesenchymal stem/stromal cells in regenerative medicine and cellular therapy

VV Maldonado, NH Patel, EE Smith, CL Barnes… - Journal of biological …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous
potential in regenerative medicine. With their immunomodulatory and regenerative …

Multiple system atrophy: recent developments and future perspectives

WG Meissner, PO Fernagut, B Dehay… - Movement …, 2019 - Wiley Online Library
Multiple system atrophy (MSA) is a rare and fatal neurodegenerative disorder characterized
by a variable combination of parkinsonism, cerebellar impairment, and autonomic …

Stem cell therapies for chronic liver diseases: progress and challenges

TT Li, ZR Wang, WQ Yao, EQ Linghu… - Stem Cells …, 2022 - academic.oup.com
Chronic liver diseases have become a significant health issue worldwide and urgently
require the development of novel therapeutic approaches, in addition to liver transplantation …

Evaluation of neurotrophic factor secreting mesenchymal stem cells in progressive multiple sclerosis

JA Cohen, FD Lublin, C Lock… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: Autologous mesenchymal stem cell neurotrophic factor–secreting cells
(NurOwn®) have the potential to modify underlying disease mechanisms in progressive …

The unified multiple system atrophy rating scale: status, critique, and recommendations

F Krismer, JA Palma, G Calandra‐Buonaura… - Movement …, 2022 - Wiley Online Library
The Unified Multiple System Atrophy Rating Scale (UMSARS) was developed almost two
decades ago as a clinical rating scale to capture multiple aspects of the disease. 1, 2 It is …

Multiple system atrophy

A Fanciulli, I Stankovic, F Krismer, K Seppi… - International Review of …, 2019 - Elsevier
Multiple system atrophy (MSA) is a sporadic, adult-onset, relentlessly progressive
neurodegenerative disorder, clinically characterized by various combinations of autonomic …

[HTML][HTML] Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions

S Kaji, T Maki, T Ishimoto, H Yamakado… - Translational …, 2020 - Springer
Multiple system atrophy (MSA) is a debilitating and fatal neurodegenerative disorder. The
disease severity warrants urgent development of disease-modifying therapy, but the disease …