Fluid transport in the brain
MK Rasmussen, H Mestre… - Physiological …, 2022 - journals.physiology.org
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …
wakefulness, the brain is geared fully toward processing information and behaving, while …
History and progress of hypotheses and clinical trials for Alzheimer's disease
PP Liu, Y Xie, XY Meng, JS Kang - Signal transduction and targeted …, 2019 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
memory loss along with neuropsychiatric symptoms and a decline in activities of daily life. Its …
[PDF][PDF] VEGF in signaling and disease: beyond discovery and development
The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our
understanding of vasculogenesis and angiogenesis during development and physiological …
understanding of vasculogenesis and angiogenesis during development and physiological …
Exosomal long noncoding RNA LNMAT2 promotes lymphatic metastasis in bladder cancer
C Chen, Y Luo, W He, Y Zhao, Y Kong… - The Journal of …, 2020 - Am Soc Clin Investig
Patients with bladder cancer (BCa) with clinical lymph node (LN) metastasis have an
extremely poor prognosis. VEGF-C has been demonstrated to play vital roles in LN …
extremely poor prognosis. VEGF-C has been demonstrated to play vital roles in LN …
Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI
Here, we report the existence of meningeal lymphatic vessels in human and nonhuman
primates (common marmoset monkeys) and the feasibility of noninvasively imaging and …
primates (common marmoset monkeys) and the feasibility of noninvasively imaging and …
Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials
Z Niu, R Jin, Y Zhang, H Li - Signal Transduction and Targeted Therapy, 2022 - nature.com
Lung cancer is the leading cause of cancer-related death across the world. Unlike lung
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …
adenocarcinoma, patients with lung squamous cell carcinoma (LSCC) have not benefitted …
[PDF][PDF] The meningeal lymphatic system: a new player in neurophysiology
The nature of fluid dynamics within the brain parenchyma is a focus of intensive research. Of
particular relevance is its participation in diseases associated with protein accumulation and …
particular relevance is its participation in diseases associated with protein accumulation and …
Complexation-induced resolution enhancement of 3D-printed hydrogel constructs
J Gong, CCL Schuurmans, AM Genderen… - Nature …, 2020 - nature.com
Abstract Three-dimensional (3D) hydrogel printing enables production of volumetric
architectures containing desired structures using programmed automation processes. Our …
architectures containing desired structures using programmed automation processes. Our …
Immunopathogenesis of IBD: current state of the art
HSP De Souza, C Fiocchi - Nature reviews Gastroenterology & …, 2016 - nature.com
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …
Ten years of anti-vascular endothelial growth factor therapy
N Ferrara, AP Adamis - Nature reviews Drug discovery, 2016 - nature.com
The targeting of vascular endothelial growth factor A (VEGFA), a crucial regulator of both
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …
normal and pathological angiogenesis, has revealed innovative therapeutic approaches in …