Epidemiology of Parkinson's Disease: An Update

JR Deliz, CM Tanner, P Gonzalez-Latapi - Current neurology and …, 2024 - Springer
Epidemiology of Parkinson’s Disease: An Update | Current Neurology and Neuroscience
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[HTML][HTML] Sex-divergent effects on the NAD+-dependent deacetylase sirtuin signaling across the olfactory–entorhinal–amygdaloid axis in Alzheimer's and Parkinson's …

P Cartas-Cejudo, M Lachén-Montes, I Ferrer… - Biology of sex …, 2023 - Springer
Background Smell impairment is one of the earliest features in Alzheimer's (AD) and
Parkinson's diseases (PD). Due to sex differences exist in terms of smell and olfactory …

In silico molecular docking and ADMET analysis for drug development of phytoestrogens compound with its evaluation of neurodegenerative diseases

FA Muslikh, RR Samudra, B Ma'arif… - Borneo Journal of …, 2022 - journal.umpr.ac.id
Neurodegenerative disease is one of the problems faced by postmenopausal women due to
estrogen deficiency. Phytoestrogen compounds can be used as an alternative treatment for …

[HTML][HTML] Emerging role of ABC transporters in glia cells in health and diseases of the central nervous system

M Villa, J Wu, S Hansen, J Pahnke - Cells, 2024 - mdpi.com
ATP-binding cassette (ABC) transporters play a crucial role for the efflux of a wide range of
substrates across different cellular membranes. In the central nervous system (CNS), ABC …

[HTML][HTML] Chromosomal and gonadal factors regulate microglial sex effects in the aging brain

SR Ocañas, VA Ansere, CM Kellogg, JVV Isola… - Brain research …, 2023 - Elsevier
Biological sex contributes to phenotypic sex effects through genetic (sex chromosomal) and
hormonal (gonadal) mechanisms. There are profound sex differences in the prevalence and …

2-Aminoethoxydiphenyl borate ameliorates mitochondrial dysfunctions in MPTP/MPP+ model of Parkinson's disease

B Vaidya, M Polepalli, SS Sharma, JN Singh - Mitochondrion, 2023 - Elsevier
Mitochondrial dysfunction is closely linked with the pathophysiology of several
neurodegenerative disorders including Parkinson's disease (PD). Despite several …

[HTML][HTML] Intelligence, education level, and risk of Parkinson's disease in European populations: A Mendelian randomization study

J Shi, J Tian, Y Fan, X Hao, M Li, J Li, D Ma… - Frontiers in …, 2022 - frontiersin.org
Background: A high level of education or intelligence (IQ) is reported to be a risk factor for
Parkinson's disease (PD). The purpose of this study was to systematically examine the …

Task-specific effects of biological sex and sex hormones on object recognition memories in a 6-hydroxydopamine-lesion model of Parkinson's disease in adult male …

CC Pinizzotto, A Patwardhan, D Aldarondo… - Hormones and …, 2022 - Elsevier
Many patients with Parkinson's disease (PD) experience cognitive or memory impairments
with few therapeutic options available to mitigate them. This has fueled interest in …

[HTML][HTML] Three-dimensional analysis of sex-and gonadal status-dependent microglial activation in a mouse model of Parkinson's disease

A Isenbrandt, K Coulombe, M Morissette, M Bourque… - Pharmaceuticals, 2023 - mdpi.com
Parkinson's disease (PD) is characterized by neurodegeneration and neuroinflammation.
PD prevalence and incidence are higher in men than in women and modulation of gonadal …

Sex Differences in the Speech of Persons With and Without Parkinson's Disease

N Houle, T Feaster, A Mira, K Meeks, CE Stepp - American journal of speech …, 2024 - ASHA
Background: Sex differences are apparent in the prevalence and the clinical presentation of
Parkinson's disease (PD), but their effects on speech have been less studied. Method …