Update on the pathophysiology and medical treatment of peripheral artery disease

J Golledge - Nature reviews cardiology, 2022 - nature.com
Approximately 6% of adults worldwide have atherosclerosis and thrombosis of the lower
limb arteries (peripheral artery disease (PAD)) and the prevalence is rising. PAD causes leg …

Advances in revascularization for peripheral artery disease: revascularization in PAD

JA Beckman, PA Schneider, MS Conte - Circulation research, 2021 - Am Heart Assoc
Effective revascularization of the patient with peripheral artery disease is about more than
the procedure. The approach to the patient with symptom-limiting intermittent claudication or …

[HTML][HTML] Statins and statin intensity in peripheral artery disease

M Sagris, I Katsaros, S Giannopoulos, RD Rosenberg… - Vasa, 2022 - econtent.hogrefe.com
Background: Peripheral artery disease (PAD) affects more than 202 million people
worldwide. Several studies have shown that patients with PAD are often undertreated, and …

[HTML][HTML] Amputation in diabetic foot ulcer: A treatment dilemma

RA Primadhi, R Septrina, P Hapsari… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Diabetic foot is a clinical manifestation of diabetes with a wide range of symptoms, including
ulceration, osteomyelitis, osteoarticular destruction, and gangrene, as a consequence of …

Role of lipid-lowering therapy in peripheral artery disease

AD Belur, AJ Shah, SS Virani, M Vorla… - Journal of Clinical …, 2022 - mdpi.com
Atherosclerosis is a multifactorial, lipoprotein-driven condition that leads to plaque formation
within the arterial tree, leading to subsequent arterial stenosis and thrombosis that accounts …

[HTML][HTML] Editor's Choice–European Society for Vascular Surgery (ESVS) 2023 clinical practice guidelines on antithrombotic therapy for vascular diseases

CP Twine, SK Kakkos, V Aboyans… - European Journal of …, 2023 - Elsevier
1.1. Purpose The European Society for Vascular Surgery (ESVS) has developed a series of
clinical practice guidelines for clinicians caring for patients with vascular diseases. This is …

Evidence-based recommendations for medical management of peripheral artery disease

J Golledge, A Drovandi - Journal of Atherosclerosis and Thrombosis, 2021 - jstage.jst.go.jp
Patients with lower limb artery stenosis or occlusion (peripheral artery disease; PAD) have
been determined to be at very high risk of both major adverse cardiovascular events, such …

Rivaroxaban plus aspirin versus aspirin alone after endovascular revascularization for symptomatic PAD: insights from VOYAGER PAD

J Rymer, SS Anand, E Sebastian Debus, LP Haskell… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Rivaroxaban plus aspirin compared with aspirin alone reduced major
cardiac and ischemic limb events after lower extremity revascularization (LER) in the …

Preventive therapies in peripheral arterial disease

AJ Shah, N Pavlatos, DK Kalra - Biomedicines, 2023 - mdpi.com
Atherosclerosis, while initially deemed a bland proliferative process, is now recognized as a
multifactorial-lipoprotein-mediated inflammation-driven pathway. With the rising incidence of …

[HTML][HTML] Peripheral artery disease leading to major amputation: Trends in revascularization and mortality over 18 years

L Abry, S Weiss, V Makaloski, AG Haynes… - Annals of vascular …, 2022 - Elsevier
Background Patients with peripheral artery disease (PAD) are at risk for amputation. The aim
of this study was to assess the type of revascularization prior to and the 30-day mortality rate …