Decades of research in drug targeting to the upper gastrointestinal tract using gastroretention technologies: where do we stand?

R Awasthi, GT Kulkarni - Drug delivery, 2016 - Taylor & Francis
A major constraint in oral controlled release drug delivery is that not all the drug candidates
are absorbed uniformly throughout the gastrointestinal tract (GIT). Drugs having “absorption …

Development of novel gastroretentive floating particulate drug delivery system of gliclazide

R Awasthi, GT Kulkarni - Current drug delivery, 2012 - ingentaconnect.com
The objective of present project was to improve the dissolution profile of gliclazide by
developing floating alginate beads using various biodegradable polymers like gelatin …

[HTML][HTML] Development and characterization of amoxicillin loaded floating microballoons for the treatment of Helicobacter pylori induced gastric ulcer

R Awasthi, GT Kulkarni - asian journal of pharmaceutical sciences, 2013 - Elsevier
The current communication reports in vitro characterization of the optimized hollow floating
microballoons of amoxicillin on the basis of micromeritic properties and in vitro minimum …

[PDF][PDF] Floating in-situ raft forming liquid gastroretentive drug delivery system containing poorly water-soluble drug

R Awasthi - Bulletin of Pharmaceutical Sciences Assiut …, 2021 - bpsa.journals.ekb.eg
Present work was aimed to develop a liquid in-situ raft forming floating gastroretentive
system of repaglinide using gellan gum, pectin, and sodium alginate. The formulations were …

Ionotropic cross-linked buoyant polymeric matrices for gastroretentive drug delivery

TM Serim, CT Sengel-Turk, AN Ozdemir - Ionotropic Cross-Linking of …, 2024 - Elsevier
A great interest in the design of systems to control or target the drug release as part of drug
delivery development has significantly increased over the recent years. A specific attention …

Formulation and in vitro Evaluation of Lisinopril floating Gastroretentive Tablets

A Tandon, PK Jangra - Research Journal of Pharmacy and …, 2021 - indianjournals.com
The present study was aimed to develop sustained release floating tablet containing
lisinopril by wet granulation technique. HPMC K4 M and Carbopol 934 P were used to …

Floating Drug Delivery System: As A Novel Approach for Drug Delivery

M Choudhary, C Tiwari, RK Chahar, P Malik… - Journal of Drug …, 2022 - jddtonline.info
The retention period of the drug and dosage form in the stomach is very challenging for the
treatment of gastrointestinal disease. To solve this problem and improve the efficacy and …

[PDF][PDF] Development and characterization of novel gastroretentive raft forming floating film of atenolol

N Sharma, R Awasthi - Indian Drugs, 2015 - researchgate.net
The aim of present work was to develop a gastroretentive floating raft forming film of atenolol
using solvent casting technique. The films were characterized in terms of drug-excipient …

[PDF][PDF] Controlled Release and Gastroretentive Drug Delivery Systems

R Awasthi, VK Pawar, GT Kulkarni - bspublications.net
Over the past decades we have witnessed the availability of wide range of controlled
release dosage forms in the pharmaceutical market. There are several reasons for the …