Weekly low‐dose versus three‐weekly high‐dose cisplatin for concurrent chemoradiation in locoregionally advanced non‐nasopharyngeal head and neck cancer: a …

P Szturz, K Wouters, N Kiyota, M Tahara… - The …, 2017 - academic.oup.com
Background Three‐weekly high‐dose cisplatin (100 mg/m2) is considered the standard
systemic regimen given concurrently with postoperative or definitive radiotherapy in locally …

Low-dose vs. high-dose cisplatin: lessons learned from 59 chemoradiotherapy trials in head and neck cancer

P Szturz, K Wouters, N Kiyota, M Tahara… - Frontiers in …, 2019 - frontiersin.org
In locally advanced squamous cell carcinomas of the head and neck (LA-SCCHN),
concurrent chemoradiotherapy is an integral part of multimodality management both in the …

Weekly cisplatin plus radiation for postoperative head and neck cancer (JCOG1008): a multicenter, noninferiority, phase II/III randomized controlled trial

N Kiyota, M Tahara, J Mizusawa, T Kodaira… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE The standard treatment for postoperative high-risk locally advanced squamous
cell carcinoma of the head and neck (LA-SCCHN) is chemoradiotherapy with 3-weekly …

Once-a-week versus once-every-3-weeks cisplatin chemoradiation for locally advanced head and neck cancer: a phase III randomized noninferiority trial

V Noronha, A Joshi, VM Patil, J Agarwal… - Journal of Clinical …, 2018 - ascopubs.org
Purpose Chemoradiation with cisplatin 100 mg/m2 given once every 3 weeks is the
standard of care in locally advanced head and neck squamous cell cancer (LAHNSCC) …

Cisplatin eligibility issues and alternative regimens in locoregionally advanced head and neck cancer: recommendations for clinical practice

P Szturz, V Cristina, RG Herrera Gómez… - Frontiers in …, 2019 - frontiersin.org
Well-designed randomized trials provide the highest level of scientific evidence to guide
clinical decision making. In chemoradiotherapy of locally advanced squamous cell …

Disease‐induced and treatment‐induced alterations in body composition in locally advanced head and neck squamous cell carcinoma

ACH Willemsen, A Hoeben, RI Lalisang… - Journal of cachexia …, 2020 - Wiley Online Library
Background Chemoradiation or bioradiation treatment (CRT/BRT) of locally advanced head
and neck squamous cell carcinoma (LAHNSCC) comes with high toxicity rates, often leading …

[HTML][HTML] Impact of cisplatin dose intensity on human papillomavirus-related and-unrelated locally advanced head and neck squamous cell carcinoma

A Spreafico, SH Huang, W Xu, R Granata… - European Journal of …, 2016 - Elsevier
Aim The aim is to evaluate the impact of cisplatin dose modification on outcomes of human
papillomavirus (HPV)-related (HPV+) and HPV-unrelated (HPV−) locally advanced head …

[HTML][HTML] Disease outcome and associated factors after definitive platinum based chemoradiotherapy for advanced stage HPV-negative head and neck cancer

RH de Roest, M van der Heijden… - Radiotherapy and …, 2022 - Elsevier
Background Definitive concomitant cisplatin-based chemoradiotherapy (CRT) is the current
gold standard for most patients with advanced stage head and neck squamous cell …

A pilot study of a smartphone-based monitoring intervention on head and neck cancer patients undergoing concurrent chemo-radiotherapy

EM Zini, G Lanzola, S Quaglini, P Bossi, L Licitra… - International journal of …, 2019 - Elsevier
Background Multidisciplinary treatment for head and neck carcinoma offers the best curative
results but generates acute toxicities, which negatively affect both patients' quality of life and …

Electrospun nanofibers for local anticancer therapy: Review of in vivo activity

L Poláková, J Širc, R Hobzová, AI Cocârță… - International journal of …, 2019 - Elsevier
Currently, chemotherapy is the most common treatment for oncological diseases. Systemic
administration of chemotherapeutics provides an easy and effective distribution of the active …