The midcycle surge of LH sets in motion interconnected networks of signaling cascades to
bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators …

Background Decidualization of the human endometrium, which involves a dramatic
morphological and functional differentiation of human endometrial stromal cells (ESC s), is …

Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

The safety of progestogens as a class has come under increased scrutiny after the
publication of data from the Women's Health Initiative trial, particularly with respect to breast …

Progesterone is commonly considered as a female reproductive hormone and is well-known
for its role in pregnancy. It is less well appreciated that progesterone and its metabolite …

Across the Western World there is an increasing trend to postpone childbearing.
Consequently, the negative influence of age on oocyte quality may lead to a difficulty in …

Trophoblasts, the specialized cells of the placenta, play a major role in implantation and
formation of the maternal-fetal interface. Through an unusual differentiation process …

The Fourth Edition of Knobil & Neill continues to serve as a reference aid for research, to
provide the historical context to current research, and most importantly as an aid for …

Emerging data indicate that progesterone has multiple non-reproductive functions in the
central nervous system to regulate cognition, mood, inflammation, mitochondrial function …

Ligands for the nuclear receptor superfamily control many aspects of biology, including
development, reproduction, and homeostasis, through regulation of the transcriptional …