The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Pain associated with mechanical, chemical, and thermal heat stimulation of the ocular
surface is mediated by trigeminal ganglion neurons, while cold thermoreceptors detect …

For the last 20 years, a great amount of evidence has accumulated through epidemiological
studies that most of the dry eye disease encountered in daily life, especially in video display …

In the field of predictive, preventive and personalised medicine, researchers are keen to
identify novel and reliable ways to predict and diagnose disease, as well as to monitor …

Most patients with chronic dry eye disease (DED) have episodic flares, which can be
triggered by a variety of activities and environmental stresses. These flares are typically …

Sjögren's syndrome (SS) is a chronic autoimmune disease that primarily affects the exocrine
glands, resulting in their functional impairment. In SS, lymphocytic infiltration of salivary and …

Dry eye has gained recognition as a public health problem given its prevalence, morbidity,
and cost implications. Dry eye can have a variety of symptoms including blurred vision …

Dry eye is one of the most commonly encountered problems in ophthalmology. Signs can
include punctate epithelial erosions, hyperemia, low tear lakes, rapid tear break-up time …

Background—It is recognized that inflammation is an underlying cause of dry eye disease
(DED), with cytokine release involved. We systematically reviewed literature with meta …

As the biological alarm of impending or actual tissue damage, pain is essential for our
survival. However, when it is initiated and/or sustained by dysfunctional elements in the …