Neuroprotective role of the Nrf2 pathway in subarachnoid haemorrhage and its therapeutic potential

A Zolnourian, I Galea, D Bulters - Oxidative medicine and …, 2019 - Wiley Online Library
The mechanisms underlying poor outcome following subarachnoid haemorrhage (SAH) are
complex and multifactorial. They include early brain injury, spreading depolarisation …

The promises and challenges of erythropoietin for treatment of Alzheimer's disease

J Sun, JM Martin, V Vanderpoel, RK Sumbria - Neuromolecular medicine, 2019 - Springer
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the world, and
intracellular neurofibrillary tangles and extracellular amyloid-beta protein deposits represent …

Widespread expression of erythropoietin receptor in brain and its induction by injury

C Ott, H Martens, I Hassouna, B Oliveira, C Erck… - Molecular …, 2015 - Springer
Erythropoietin (EPO) exerts potent neuroprotective, neuroregenerative and procognitive
functions. However, unequivocal demonstration of erythropoietin receptor (EPOR) …

Zinc supplementation stimulates red blood cell formation in rats

YH Chen, HL Feng, SS Jeng - International journal of molecular sciences, 2018 - mdpi.com
In rats, mice, and humans, it is known that zinc deficiency may be related to anemia, and
zinc supplementation influences hemoglobin production. Our previous studies indicate that …

Emerging role of nutritional short-chain fatty acids (SCFAs) against cancer via modulation of hematopoiesis

M Thiruvengadam, U Subramanian… - Critical Reviews in …, 2023 - Taylor & Francis
The understanding of gut microbiota has emerged as a significant frontier in development of
strategies to maintain normal human body's homeostasis and preventing the disease …

Repopulation of porcine kidney scaffold using porcine primary renal cells

M Abolbashari, SM Agcaoili, MK Lee, IK Ko… - Acta biomaterialia, 2016 - Elsevier
The only definitive treatment for end stage renal disease is renal transplantation, however
the current shortage of organ donors has resulted in a long list of patients awaiting …

Erythropoietin modulates bone marrow stromal cell differentiation

S Suresh, LF de Castro, S Dey, PG Robey… - Bone research, 2019 - nature.com
Erythropoietin is essential for bone marrow erythropoiesis and erythropoietin receptor on
non-erythroid cells including bone marrow stromal cells suggests systemic effects of …

Mechanisms and Cardiorenal Complications of Chronic Anemia in People with HIV

K Kamvuma, BM Hamooya, S Munsaka, SK Masenga… - Viruses, 2024 - mdpi.com
Chronic anemia is more prevalent in people living with HIV (PLWH) compared to the general
population. The mechanisms that drive chronic anemia in HIV are multifaceted and include …

[HTML][HTML] Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review

I Silva, C Alípio, R Pinto, V Mateus - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Erythropoietin (EPO) is a hypoxia-induced hormone produced in adult kidneys with
erythropoietic and non-erythropoietic effects. In vivo studies represent an important role to …

[HTML][HTML] Anemia and heart failure: A narrative review

SW Siddiqui, T Ashok, N Patni, M Fatima, A Lamis… - Cureus, 2022 - ncbi.nlm.nih.gov
Anemia in heart failure patients is a relatively common finding and has been linked with an
increased risk of hospital admissions, morbidities, and significant mortality making its …