Protein and peptide conjugates have become an important component of therapeutic and
diagnostic medicine. These conjugates are primarily designed to improve pharmacokinetics …

Biologics have been used increasingly in the treatment and supportive care of cancer;
however, their high cost places a significant burden on healthcare systems. The expiration of …

We have observed 87 children aged from 5 to 12 years with a diagnosis of chronic
pyelonephritis (CHP). With the detection of the functional state of the kidney complex clinical …

Background Recent studies regarding the effects of erythropoietin (EPO) for treating
traumatic brain injury (TBI) have been inconsistent. This study conducts a meta-analysis of …

Biologicals have become an integral part of cancer treatment both as therapeutic agents and
as supportive care agents. It is important to know that biologics are large, complex molecular …

The present review provides a comprehensive overview on the erythropoietic and non-
erythropoietic effects of rHuEpo on human sport performance, paying attention to quantifying …

Assessment of critical quality attributes of the biopharmaceutical erythropoietin (EPO) prior
to product release requires the use of several analytical methods. We developed an MS …

Traumatic brain injury (TBI) is one of the leading causes of morbidity, disability and mortality
across all age groups globally. Currently, only palliative treatments exist, but these are …

Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are currently under clinical
development for treating anemia in chronic kidney disease (CKD), but it is important to …

Patients with renal anemia are frequently treated with erythropoiesis-stimulating agents
(ESAs), which are dynamically dosed in order to stabilize blood hemoglobin levels within a …