[HTML][HTML] Vascular pathologies in chronic kidney disease: pathophysiological mechanisms and novel therapeutic approaches

P Düsing, A Zietzer, PR Goody, MR Hosen… - Journal of molecular …, 2021 - Springer
Cardiovascular disease (CVD) is a major cause of death in patients with chronic kidney
disease (CKD). Both conditions are rising in incidence as well as prevalence, creating poor …

[HTML][HTML] Signaling pathways involved in vascular smooth muscle cell calcification during hyperphosphatemia

J Voelkl, F Lang, KU Eckardt, K Amann… - Cellular and Molecular …, 2019 - Springer
Medial vascular calcification has emerged as a putative key factor contributing to the
excessive cardiovascular mortality of patients with chronic kidney disease (CKD) …

Osteoporosis and chronic kidney disease–mineral and bone disorder (CKD-MBD): back to basics

M Pazianas, PD Miller - American Journal of Kidney Diseases, 2021 - Elsevier
Osteoporosis is defined as a skeletal disorder of compromised bone strength predisposing
those affected to an elevated risk of fracture. However, based on bone histology …

Effect of treating hyperphosphatemia with lanthanum carbonate vs calcium carbonate on cardiovascular events in patients with chronic kidney disease undergoing …

H Ogata, M Fukagawa, H Hirakata, T Kagimura… - Jama, 2021 - jamanetwork.com
Importance Among patients with hyperphosphatemia undergoing dialysis, it is unclear
whether non–calcium-based phosphate binders are more effective than calcium-based …

[HTML][HTML] Strategies for phosphate control in patients with CKD

FC Barreto, DV Barreto, ZA Massy… - Kidney international reports, 2019 - Elsevier
Hyperphosphatemia is a common complication in patients with chronic kidney disease
(CKD), particularly in those requiring renal replacement therapy. The importance of …

Interventions to attenuate vascular calcification progression in chronic kidney disease: a systematic review of clinical trials

C Xu, ER Smith, MK Tiong, I Ruderman… - Journal of the …, 2022 - journals.lww.com
Interventions To Attenuate Vascular Calcification Progressio... : Journal of the American
Society of Nephrology Interventions To Attenuate Vascular Calcification Progression in Chronic …

[HTML][HTML] A randomized trial of tenapanor and phosphate binders as a dual-mechanism treatment for hyperphosphatemia in patients on maintenance dialysis (AMPLIFY …

PE Pergola, DP Rosenbaum, Y Yang… - Journal of the …, 2021 - journals.lww.com
Background Hyperphosphatemia is associated with cardiovascular morbidity and mortality
in patients receiving maintenance dialysis. It is unknown whether combining two therapies …

[HTML][HTML] Hyperphosphatemia and cardiovascular disease

C Zhou, Z Shi, N Ouyang, X Ruan - Frontiers in Cell and …, 2021 - frontiersin.org
Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range”
are highly associated with increased cardiovascular disease risk and mortality in the general …

[HTML][HTML] The interplay between mineral metabolism, vascular calcification and inflammation in Chronic Kidney Disease (CKD): challenging old concepts with new facts

C Viegas, N Araújo, C Marreiros, D Simes - Aging (Albany NY), 2019 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) is one of the most powerful predictors of premature
cardiovascular disease (CVD), with heightened susceptibility to vascular intimal and medial …

Secondary hyperparathyroidism and adverse health outcomes in adults with chronic kidney disease

Y Xu, M Evans, M Soro, P Barany… - Clinical kidney …, 2021 - academic.oup.com
Background Secondary hyperparathyroidism (sHPT) develops frequently in patients with
chronic kidney disease (CKD). However, the burden and long-term impact of sHPT on the …