The pursuit to discover the fundamental biology and mechanisms of aging within the context
of the physical and social environment is critical to designing interventions to prevent and …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system and
common cause of non-traumatic neurological disability in young adults. The likelihood for an …

Importance In multiple sclerosis (MS), chronic active lesions, which previously could only be
detected at autopsy, can now be identified on susceptibility-based magnetic resonance …

Rare genetic variants contribute to complex disease risk; however, the abundance of rare
variants in human populations remains unknown. We explored this spectrum of variation by …

Multiple sclerosis (MS) has a strong racial and ethnic component and disproportionately
affects whites of European background. Recent incidence reports suggest an increasing rate …

Multiple sclerosis (MS) is a prevalent inflammatory disease of the central nervous system
that often leads to disability in young adults. Treatment options are limited and often only …

The heterogeneity of multiple sclerosis (MS) characteristics among various ethnic minority
populations is a topic of recent interest. However, these populations are consistently …

Abstract On average, African Americans with multiple sclerosis demonstrate higher
inflammatory disease activity, faster disability accumulation, greater visual dysfunction, more …

Objective: To investigate utility of a Multiple Sclerosis Severity Scale (MSSS)–based
classification system for comparing African American (AA) and white American (WA) multiple …

Until recently, neuromyelitis optica (NMO) was considered to be a sub-type of multiple
sclerosis (MS), which has a strong predilection for Caucasian populations, whereas NMO is …