In order to meet the high energy demand, a metabolic reprogramming occurs in cancer cells.
Its role is crucial in promoting tumor survival. Among the substrates in demand, oxygen is …

Cancer cells are well-known for adapting their metabolism to maintain high proliferation
rates and survive in unfavorable environments with low oxygen and nutritional deficiency …

Cancer alters the function of multiple organs beyond those targeted by metastasis,. Here we
show that inflammation, fatty liver and dysregulated metabolism are hallmarks of …

Cachexia remains an underdiagnosed and undertreated, complex condition which includes
'objective'components (eg inadequate food intake, weight loss, inactivity, loss of muscle …

PURPOSE To provide evidence-based guidance on the clinical management of cancer
cachexia in adult patients with advanced cancer. METHODS A systematic review of the …

Diverse inflammatory diseases, infections and malignancies are associated with wasting
syndromes. In many of these conditions, the standards for diagnosis and treatment are …

Muscle wasting is a consequence of physiological changes or a pathology characterized by
increased catabolic activity that leads to progressive loss of skeletal muscle mass and …

Cancer-associated cachexia is a disorder characterized by loss of body weight with specific
losses of skeletal muscle and adipose tissue. Cachexia is driven by a variable combination …

Cancer cachexia has long been perceived as a nutritional syndrome. However, nutritional
interventions have continued to be ineffective. With the recent recognition of the importance …

The term “cachexia” is derived from the Greek words kakos (bad) and hexis (habit).
Cachexia is a malnutrition associated with chronic diseases such as cancer, chronic heart …