Pair correlation microscopy reveals the role of nanoparticle shape in intracellular transport and site of drug release

E Hinde, K Thammasiraphop, HTT Duong… - Nature …, 2017 - nature.com
Nanoparticle size, surface charge and material composition are known to affect the uptake of
nanoparticles by cells. However, whether nanoparticle shape affects transport across …

The use of human umbilical vein endothelial cells (HUVECs) as an in vitro model to assess the toxicity of nanoparticles to endothelium: a review

Y Cao, Y Gong, L Liu, Y Zhou, X Fang… - Journal of Applied …, 2017 - Wiley Online Library
With the rapid development of nanotechnologies, nanoparticles (NPs) are increasingly
produced and used in many commercial products, which could lead to the contact of human …

Non-spherical micro-and nanoparticles for drug delivery: Progress over 15 years

N Kapate, JR Clegg, S Mitragotri - Advanced Drug Delivery Reviews, 2021 - Elsevier
Shape of particulate drug carries has been identified as a key parameter in determining their
biological outcome. In this review, we analyze the field of particle shape as it shifts from …

Facile synthesis of uniform virus-like mesoporous silica nanoparticles for enhanced cellular internalization

W Wang, P Wang, X Tang, AA Elzatahry… - ACS central …, 2017 - ACS Publications
The low-efficiency cellular uptake property of current nanoparticles greatly restricts their
application in the biomedical field. Herein, we demonstrate that novel virus-like mesoporous …

Smart polymeric hydrogels for cartilage tissue engineering: a review on the chemistry and biological functions

N Eslahi, M Abdorahim, A Simchi - Biomacromolecules, 2016 - ACS Publications
Stimuli responsive hydrogels (SRHs) are attractive bioscaffolds for tissue engineering. The
structural similarity of SRHs to the extracellular matrix (ECM) of many tissues offers great …

Shape and size-dependent immune response to antigen-carrying nanoparticles

S Kumar, AC Anselmo, A Banerjee… - Journal of Controlled …, 2015 - Elsevier
The immune system has evolved to recognize and respond to a wide variety of pathogens
and produce distinct immune responses against diverse pathogenic structures. Despite …

Understanding and exploiting nanoparticles' intimacy with the blood vessel and blood

MI Setyawati, CY Tay, D Docter, RH Stauber… - Chemical Society …, 2015 - pubs.rsc.org
While the blood vessel is seldom the target tissue, almost all nanomedicine will interact with
blood vessels and blood at some point of time along its life cycle in the human body …

Modulation of the cellular uptake of DNA origami through control over mass and shape

MMC Bastings, FM Anastassacos, N Ponnuswamy… - Nano …, 2018 - ACS Publications
Designer nanoparticles with controlled shapes and sizes are increasingly popular vehicles
for therapeutic delivery due to their enhanced cell-delivery performance. However, our …

Effects of morphology and size of nanoscale drug carriers on cellular uptake and internalization process: a review

W Zhang, R Taheri-Ledari, F Ganjali… - RSC …, 2023 - pubs.rsc.org
In the field of targeted drug delivery, the effects of size and morphology of drug nanocarriers
are of great importance and need to be discussed in depth. To be concise, among all the …

The influence of nanoparticle properties on oral bioavailability of drugs

Y Wang, C Pi, X Feng, Y Hou, L Zhao… - International journal of …, 2020 - Taylor & Francis
Oral administration has been the most common therapeutic regimen in various diseases
because of its high safety, convenience, lower costs, and high compliance of patients …