Biomedical applications of pH-responsive amphiphilic polymer nanoassemblies

SR Mane, A Sathyan… - ACS Applied Nano …, 2020 - ACS Publications
In recent years, polymer nanoassemblies have played an important role in the
biopharmaceuticals field. Polymers that form different molecular architectures during a self …

Soft discoidal polymeric nanoconstructs resist macrophage uptake and enhance vascular targeting in tumors

J Key, AL Palange, F Gentile, S Aryal, C Stigliano… - ACS …, 2015 - ACS Publications
Most nanoparticles for biomedical applications originate from the self-assembling of
individual constituents through molecular interactions and possess limited geometry control …

[HTML][HTML] An insight to brain targeting utilizing polymeric nanoparticles: effective treatment modalities for neurological disorders and brain tumor

Annu, A Sartaj, Z Qamar, S Md… - … in Bioengineering and …, 2022 - frontiersin.org
The delivery of therapeutic molecules to the brain remains an unsolved problem to the
researchers due to the existence of the blood–brain barrier (BBB), which halts the entry of …

Nanomaterials for engineering stem cell responses

P Kerativitayanan, JK Carrow… - Advanced healthcare …, 2015 - Wiley Online Library
Recent progress in nanotechnology has stimulated the development of multifunctional
biomaterials for tissue engineering applications. Synergistic interactions between …

[HTML][HTML] Bioactive nanoparticles for cancer immunotherapy

S Poilil Surendran, MJ Moon, R Park… - International journal of …, 2018 - mdpi.com
Currently, immunotherapy is considered to be one of the effective treatment modalities for
cancer. All the developments and discoveries in this field up to the recent Nobel Prize add to …

[HTML][HTML] Size matters for in vitro gene delivery: investigating the relationships among complexation protocol, transfection medium, size and sedimentation

D Pezzoli, E Giupponi, D Mantovani, G Candiani - Scientific reports, 2017 - nature.com
Although branched and linear polyethylenimines (bPEIs and lPEIs) are gold standard
transfectants, a systematic analysis of the effects of the preparation protocol of polyplexes …

Bioinspired polymeric nanocomposites for regenerative medicine

JK Carrow, AK Gaharwar - Macromolecular Chemistry and …, 2015 - Wiley Online Library
The design and fabrication of bioinspired nanomaterials for tissue‐engineering applications
requires a fundamental understanding of the interactions between polymers, nanostructures …

[HTML][HTML] Biological nanoparticles in vaccine development

SM Curley, D Putnam - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Vaccines represent one of the most successful public health initiatives worldwide. However,
despite the vast number of highly effective vaccines, some infectious diseases still do not …

Nanoparticle–cell interaction: a cell mechanics perspective

D Septiadi, F Crippa, TL Moore… - Advanced …, 2018 - Wiley Online Library
Progress in the field of nanoparticles has enabled the rapid development of multiple
products and technologies; however, some nanoparticles can pose both a threat to the …

Engineering nanoparticles to overcome barriers to immunotherapy

R Toy, K Roy - Bioengineering & translational medicine, 2016 - Wiley Online Library
Advances in immunotherapy have led to the development of a variety of promising
therapeutics, including small molecules, proteins and peptides, monoclonal antibodies, and …