Deformable microparticles for shuttling nanoparticles to the vascular wall

MB Fish, AL Banka, M Braunreuther, CA Fromen… - Science …, 2021 - science.org
Vascular-targeted drug carriers must localize to the wall (ie, marginate) and adhere to a
diseased endothelium to achieve clinical utility. The particle size has been reported as a …

Limits and challenges in using transport inhibitors to characterize how nano-sized drug carriers enter cells

V Francia, C Reker-Smit, G Boel, A Salvati - Nanomedicine, 2019 - Taylor & Francis
Aim: In this work we illustrate limits and challenges associated with the use of
pharmacological inhibitors to study how nanomedicines enter cells and show how such …

Features of Anisotropic Drug Delivery Systems

V Kudryavtseva, GB Sukhorukov - Advanced Materials, 2024 - Wiley Online Library
Natural materials are anisotropic. Delivery systems occurring in nature, such as viruses,
blood cells, pollen, and many others, do have anisotropy, while delivery systems made …

Cellular uptake and dynamics of unlabeled freestanding silicon nanowires

JF Zimmerman, R Parameswaran, G Murray… - Science …, 2016 - science.org
The ability to seamlessly merge electronic devices with biological systems at the cellular
length scale is an exciting prospect for exploring new fundamental cell biology and in …

Shape control in engineering of polymeric nanoparticles for therapeutic delivery

JM Williford, JL Santos, R Shyam, HQ Mao - Biomaterials science, 2015 - pubs.rsc.org
Nanoparticle-mediated delivery of therapeutics holds great potential for the diagnosis and
treatment of a wide range of diseases. Significant advances have been made in the design …

Polymeric micro/nanoparticles: Particle design and potential vaccine delivery applications

H Yue, G Ma - Vaccine, 2015 - Elsevier
Particle based adjuvant showed promising signs on delivering antigen to immune cells and
acting as stimulators to elicit preventive or therapeutic response. Nevertheless, the wide size …

Role of particle shape on efficient and organ-based drug delivery

S Nejati, EM Vadeghani, S Khorshidi… - European Polymer …, 2020 - Elsevier
Encapsulation of drugs in nano-and microparticles has been known as a promising
approach for efficient drug delivery. It has been well established that adjusting the …

Advances in design and applications of polymer brush modified anisotropic particles

SS Pradhan, S Saha - Advances in Colloid and Interface Science, 2022 - Elsevier
Current advancements in the creation of anisotropy in particles and their surface
modification with polymer brushes have established a new class of hybrid materials termed …

Chitosan-based nano-formulation enhances the anticancer efficacy of hesperetin

LM Lazer, B Sadhasivam, K Palaniyandi… - International journal of …, 2018 - Elsevier
Cancer is one of the major causes of increased morbidity and mortality in modern society.
Colorectal cancer is the third leading cause for cancer related death worldwide. Current …

Current challenges toward in vitro cellular validation of inorganic nanoparticles

M Henriksen-Lacey, S Carregal-Romero… - Bioconjugate …, 2017 - ACS Publications
An impressive development has been achieved toward the production of well-defined
“smart” inorganic nanoparticles, in which the physicochemical properties can be controlled …