A study was carried out to investigate whether the action of triclabendazole sulphoxide
(TCBZ. SO) against the liver fluke, Fasciola hepatica is altered by inhibition of P-glycoprotein …

Screening of vaccine or drug target in parasitic helminth is hindered by lack of robust tool for
functional studies of parasite protein which account for the availability of only a few anti …

3 Development of Fasciola hepatica in the Mammalian Host Page 1 © CAB International
2022. Fasciolosis, 2nd Edition (ed. JP Dalton) DOI: 10.1079/9781789246162.0003 65 3.1 …

First chapter of the present book deals with the introduction of fasciolosis disease, their
history, overall status, economic impact on livestocks and milk production. Life cycle of …

A study has been carried out to investigate whether the action of triclabendazole (TCBZ)
against Fasciola hepatica is altered by the inhibition of P-glycoprotein (Pgp)-linked drug …

The binding of drugs to plasma proteins–especially serum albumin–is an important factor in
controlling the availability and distribution of these drugs. In this study we have investigated …

A major concern for helminth parasite control in human and animal health is the
development of anthelmintic resistance. The mutations that lead to such resistance do so in …

The trematode Schistosoma mansoni is a causative agent of schistosomiasis, the second
most common parasitic disease of humans after malaria. Calcium homeostasis and calcium …

Fascioliasis causes important economic losses in ruminant species all over the world. Its
control is largely based on the use of the flukicidal compound triclabendazole (TCBZ) …

Schistosomiasis is one of the neglected diseases causing considerable morbidity and
mortality throughout the world. Microtubules with its main component, tubulin play a vital role …