The RhoGTPases, with RhoA, Cdc42 and Rac being major members, are a group of key
ubiquitous proteins present in all eukaryotic organisms that subserve such important …

Among the seventeen species of the Gram-negative genus Yersinia, three have been shown
to be virulent and pathogenic to humans and animals—Y. enterocolitica, Y …

The recent and dramatic rise of antibiotic resistance among bacterial pathogens underlies
the fear that standard treatments for infectious disease will soon be largely ineffective …

Bartonella spp. are facultative intracellular bacteria that typically cause a long-lasting
intraerythrocytic bacteremia in their mammalian reservoir hosts, thereby favoring …

Yersinia pestis, the etiologic agent of plague, utilizes a type III secretion system (T3SS) to
subvert the defenses of its mammalian hosts. T3SSs are complex nanomachines that allow …

Yersinia (Y.) enterocolitica, an etiological agent of yersiniosis, is a bacterium whose
pathogenicity is determined, among other things, by its ability to produce toxins. The aim of …

Intimin and invasin are adhesins and central virulence factors of attaching and effacing
bacteria, such as enterohaemorrhagic Escherichia coli, and enteropathogenic Yersiniae …

Type III secretion systems (T3SS) play a crucial role for virulence in many Gram-negative
bacteria. After tight bacterial contact to host cells, the T3SS injects effector proteins into the …

Highlights•Cell surface components mediate resistance of Yersinia to extracellular immune
factors.•Interaction between Yersinia and host cells promotes dissemination and drives …

Yersinia spp. are non-spore-forming Gram-negative bacilli. They comprise only three
species known to cause disease in humans, namely Y. pestis, Y. enterocolitica and Y …