The incidence and mortality of squamous cell carcinoma of the anus has been gradually
increasing globally over the last few decades. The evolution of different modalities, including …

The development of cancer is a multifactorial phenomenon, while it constitutes a major
global health problem. Viruses are an important factor that is involved in tumorigenesis and …

Cancer-associated fibroblasts (CAFs) are actively involved in cancer progression through
generating extracellular matrix and orchestrating the crosstalk within the tumor …

The lack of safe and efficient therapeutic agent delivery platforms restricts combined
therapy's effect, and combined cancer therapy's multi-component delivery effect needs …

Original research: Biomarkers of pembrolizumab efficacy in advanced anal squamous cell
carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders - PMC Back …

Abstract Programmed death-ligand 1 (PD-L1) is overexpressed in squamous cervical cancer
(SCC) and can be used for targeted immunotherapy. The highest mortality rates of SCC are …

Simple Summary Colorectal cancer is a frequent and lethal neoplasm. The tumor often
creates new vessels to grow and spread—a process called 'angiogenesis'. Therefore, drugs …

Colorectal cancer (CRC) intricacies, involving dysregulated cellular processes and
programmed cell death (PCD), are explored in the context of N6-methyladenosine (m6A) …

Background Outcomes of chemo-radiation (CRT) for anal cancer in Middle East and North
Africa (MENA) are scarce. We aim to report treatment outcomes for anal cancer treated at …

Background Programmed death-ligand 1 (PD-L1) expression has been shown to be
prognostic in many cancer types and used in consideration of checkpoint inhibitor …