The current global health threat by the novel coronavirus disease 2019 (COVID-19) requires
an urgent deployment of advanced therapeutic options available. The role of …

Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease
that have shown promise in laboratory models of disease and early clinical trials. In contrast …

Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of
different materials and adjustment of their physical and chemical properties, nanoparticles …

The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …

The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Background & aims In celiac disease (CeD), gluten induces immune activation, leading to
enteropathy. TAK-101, gluten protein (gliadin) encapsulated in negatively charged poly (dl …

The main function of the immune system in health is to protect the host from infection by
microbes and parasites. Because immune responses to nonself bear the risk of unleashing …

The development of therapeutic approaches for the induction of robust, long-lasting and
antigen-specific immune tolerance remains an important unmet clinical need for the …

In the last decade, the interest in ferritin-based vaccines has been increasing due to their
safety and immunogenicity. Candidates against a wide range of pathogens are now on …

Polymers, lipids, scaffolds, microneedles, and other biomaterials are rapidly emerging as
technologies to improve the efficacy of vaccines against infectious disease and …