[HTML][HTML] Effectiveness and safety of immunotherapy in NSCLC patients with ECOG PS score≥ 2–systematic review and meta-analysis

B Tomasik, M Bieńkowski, M Braun, S Popat… - Lung Cancer, 2021 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) are standard of care in advanced
non-small cell lung cancer (NSCLC), however their status in patients with poor performance …

[HTML][HTML] Immunotherapy rechallenge after nivolumab treatment in advanced non-small cell lung cancer in the real-world setting: a national data base analysis

MG Levra, FE Cotté, R Corre, C Calvet, AF Gaudin… - Lung Cancer, 2020 - Elsevier
Objectives Nivolumab is now a reference treatment for patients with advanced non-small cell
lung cancer (NSCLC) after failure of prior platinum-based chemotherapy. Little data are …

Impact of PD1 and PDL1 immunotherapy on non-small cell lung cancer outcomes: a systematic review

SS Kanabar, A Tiwari, V Soran, P Balendran, M Price… - Thorax, 2022 - thorax.bmj.com
Introduction Despite comprising many cancer diagnoses, few treatments are suitable for
patients with advanced non-small cell lung cancer (aNSCLC). Trials suggest blockade of …

Effectiveness and safety of nivolumab in the treatment of lung cancer patients in France: preliminary results from the real-world EVIDENS study

F Barlesi, A Dixmier, D Debieuvre, C Raspaud… - …, 2020 - Taylor & Francis
ABSTRACT EVIDENS is an ongoing, prospective, non-interventional study evaluating the
effectiveness and safety of nivolumab in lung cancer patients in France (ClinicalTrials. gov …

Immunotherapy for metastatic non-small cell lung cancer: real-world data from an academic central and Eastern European center

M Ivanović, L Knez, A Herzog, M Kovačević… - The …, 2021 - academic.oup.com
Background Immunotherapy with immune checkpoint inhibitors (ICIs) recently became the
standard treatment for patients with advanced non-small cell lung cancer (NSCLC). Here …

Safety and effectiveness of immune checkpoint inhibitors in older patients with cancer: a systematic review of 48 real-world studies

A Luciani, A Ghidini, L Dottorini, F Petrelli - Drugs & aging, 2021 - Springer
Background Over recent years, immune checkpoint inhibitors (ICIs) have changed the
clinical management and prognosis for most cancers. However, data on older patients in …

Immunotherapy use in patients with lung cancer and comorbidities

MS Von Itzstein, AS Gonugunta, HG Mayo… - The Cancer …, 2020 - journals.lww.com
Immune checkpoint inhibitor (ICI) therapy is now in widespread clinical use for the treatment
of lung cancer. Although patients with autoimmune disease and other comorbidities were …

Real-World Analysis of Nivolumab and Atezolizumab Efficacy in Previously Treated Patients with Advanced Non-Small Cell Lung Cancer

M Alonso-García, A Sánchez-Gastaldo… - Pharmaceuticals, 2022 - mdpi.com
Nivolumab (anti-PD-1 antibody) and atezolizumab (anti-PD-L1 antibody) have shown
superior survival outcomes and improved adverse effects compared to standard …

[HTML][HTML] Current state of knowledge on immunotherapy in ECOG PS 2 patients. A systematic review

D Mojsak, B Kuklińska, Ł Minarowski… - Advances in Medical …, 2021 - Elsevier
Abstract Background Patients with Eastern Cooperative Oncology Group Performance
Status 2 (ECOG PS 2) are not included in most randomized clinical trials and registry …

Lymphocyte-activated gene-3 (LAG3) protein expressed in tumor-infiltrating lymphocytes of colorectal cancer

J Xu, D Shen, T Zhang, J Wang, W De… - Polish Journal of …, 2021 - termedia.pl
Immunotherapy can reverse tumor immune escape by suppressing immune checkpoints.
Lymphocyte activation gene 3 (LAG3) is an important checkpoint and its role in colorectal …