Pyroptosis and inflammasomes in diabetic wound healing

X Mu, X Wu, W He, Y Liu, F Wu, X Nie - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetic wound is one of the complications of diabetes and is not easy to heal. It often
evolves into chronic ulcers, and severe patients will face amputation. Compared with normal …

Inhibition of the pyroptosis-associated inflammasome pathway: The important potential mechanism of ginsenosides in ameliorating diabetes and its complications

P Liu, Z Zhang, Y Cai, Y Yang, J Yuan… - European Journal of …, 2023 - Elsevier
Diabetes mellitus (DM) and its complications have become an important global public health
issue, affecting human health and negatively impacting life and lifespan. Pyroptosis is a …

The impact of neurotransmitters on the neurobiology of neurodegenerative diseases

SE Davis, AB Cirincione, AC Jimenez-Torres… - International Journal of …, 2023 - mdpi.com
Neurodegenerative diseases affect millions of people worldwide. Neurodegenerative
diseases result from progressive damage to nerve cells in the brain or peripheral nervous …

Molecular mechanisms and roles of pyroptosis in acute lung injury

T Wei, C Zhang, Y Song - Chinese Medical Journal, 2022 - mednexus.org
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), which are
characterized by excessive inflammation and accompanied by diffuse injury of alveoli, can …

Transcriptome profiling and differential expression analysis of altered immune-related genes in goldfish (Carassius auratus) infected with Aeromonas hydrophila

M Nawaz, M Gouife, S Zhu, X Yue, K Huang… - Fish & Shellfish …, 2023 - Elsevier
Goldfish (Carassius auratus) have been employed as a model organism to investigate the
innate immune system and host-pathogen interactions. A Gram-negative bacterium called …

Relationship between pyroptosis-mediated inflammation and the pathogenesis of prostate disease

M Zhao, J Guo, QH Gao, H Wang, F Wang… - Frontiers in …, 2023 - frontiersin.org
The largest solid organ of the male genitalia, the prostate gland, is comprised of a variety of
cells such as prostate epithelial cells, smooth muscle cells, fibroblasts, and endothelial cells …

Extracellular vesicles of Weizmannia coagulans lilac-01 reduced cell death of primary microglia and increased mitochondrial content in dermal fibroblasts in vitro

K Minamida, T Taira, M Sasaki… - Bioscience …, 2024 - academic.oup.com
We investigated the properties of extracellular vesicles from the probiotic Weizmannia
coagulans lilac-01 (Lilac-01EVs). The phospholipids in the Lilac-01EV membrane were …

Thermal Proteome Profiling Strategy Identifies CNPY3 as a Cellular Target of Gambogic Acid for Inducing Prostate Cancer Pyroptosis

XW Zhang, L Li, M Liao, D Liu, A Rehman… - Journal of Medicinal …, 2024 - ACS Publications
There is an urgent requirement to acquire a comprehensive comprehension of novel
therapeutic targets for prostate cancer to facilitate the development of medications with …

[HTML][HTML] Necroptosis contributes to non-alcoholic fatty liver disease pathoetiology with promising diagnostic and therapeutic functions

HJ Sun, B Jiao, Y Wang, YH Zhang… - World Journal of …, 2024 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent type of chronic liver disease.
However, the disease is underappreciated as a remarkable chronic disorder as there are …

MiR-195-5p is involved in testicular ischemia/reperfusion injury by directly targeting PELP1 and regulating spermatogonia pyroptosis

KX He, L Xu, JZ Ning, F Cheng - International Immunopharmacology, 2023 - Elsevier
Background and objective Ischemia/reperfusion injury (IRI), which is characterized by
testicular torsion and causes permanent impairment of spermatogenic function, is linked with …