Nano-enabled colorectal cancer therapy

Q Pan, X Fan, L Xie, D Wu, R Liu, W Gao, K Luo… - Journal of Controlled …, 2023 - Elsevier
Colorectal cancer (CRC), one of the most common and deadliest diseases worldwide, poses
a great health threat and social burden. The clinical treatments of CRC encompassing …

The microbiome and rise of early-onset cancers: knowledge gaps and research opportunities

K Mima, T Hamada, K Inamura, H Baba, T Ugai… - Gut …, 2023 - Taylor & Francis
Accumulating evidence indicates an alarming increase in the incidence of early-onset
cancers, which are diagnosed among adults under 50 years of age, in the colorectum …

[HTML][HTML] Evaluating AI in medicine: a comparative analysis of expert and ChatGPT responses to colorectal cancer questions

W Peng, Y Feng, C Yao, S Zhang, H Zhuo, T Qiu… - Scientific Reports, 2024 - nature.com
Colorectal cancer (CRC) is a global health challenge, and patient education plays a crucial
role in its early detection and treatment. Despite progress in AI technology, as exemplified by …

[HTML][HTML] Acetylcholinesterase inhibition protects against trastuzumab-induced cardiotoxicity through reducing multiple programmed cell death pathways

T Khuanjing, C Maneechote, B Ongnok… - Molecular …, 2023 - Springer
Abstract Background Trastuzumab (Trz)-induced cardiotoxicity (TIC) is one of the most
common adverse effects of targeted anticancer agents. Although oxidative stress …

Progresses in biomarkers for cancer immunotherapy

X Lin, C Zong, Z Zhang, W Fang, P Xu - MedComm, 2023 - Wiley Online Library
Currently, checkpoint inhibitor‐based immunotherapy has emerged as prevailing treatment
modality for diverse cancers. However, immunotherapy as a first‐line therapy has not …

Vagus nerve stimulation and acetylcholinesterase inhibitor donepezil provide cardioprotection against trastuzumab-induced cardiotoxicity in rats by attenuating …

T Khuanjing, C Maneechote, B Ongnok… - Biochemical …, 2023 - Elsevier
Trastuzumab (Trz) is a targeted anticancer drug for human epidermal growth factor receptor
2 (HER2)-positive tumors, as Trz-induced cardiotoxicity (TIC) is commonly observed in Trz …

Therapeutic and diagnostic applications of antisense peptide nucleic acids

V MacLelland, M Kravitz, A Gupta - Molecular Therapy-Nucleic Acids, 2023 - cell.com
Peptide nucleic acids (PNA) are synthetic nucleic acid analogues with a neutral N-(2-
aminoethyl) glycine backbone. PNA possess unique physicochemical characteristics such …

[HTML][HTML] EphA2 as a phase separation protein associated with ferroptosis and immune cell infiltration in colorectal cancer

Y Li, Q Peng, L Wang - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Colorectal cancer is one of the most common malignant tumors in the digestive system, and
its high incidence and metastasis rate make it a terrible killer that threatens human health. In …

[HTML][HTML] A multi-omics overview of colorectal cancer to address mechanisms of disease, metastasis, patient disparities and outcomes

G Yang, X Yu, DJ Weisenberger, T Lu, G Liang - Cancers, 2023 - mdpi.com
Simple Summary Human colorectal cancer (CRC) is a global health burden, most notably for
minority populations. While screening tools have helped improve disease detection and …

[HTML][HTML] The prognostic role of p53 mutations in metastatic colorectal cancer: A systematic review and meta-analysis

A Ottaiano, M Santorsola, M Capuozzo, F Perri… - Critical Reviews in …, 2023 - Elsevier
Introduction P53 is one of the most frequently mutated genes in colorectal cancer (CRC).
The present study was undertaken to provide a solid estimate of the prognostic value of p53 …